Effects of dietary cold-pressed turnip rapeseed oil and butter on serum lipids, oxidized LDL and arterial elasticity in men with metabolic syndrome
Palomäki A, Pohjantähti-Maaroos H, Wallenius M, Kankkunen P, Aro H, Husgafvel S, Pihlava JM, Oksanen K
Lipids in health and disease · 19 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Randomized controlled trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Not stated
Who paid for it
- Funding
- Industry funded
- Nonprofit
- Suomen Kulttuurirahasto
- Nonprofit
- Hämeen Rahasto
Based on 2 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2010-12-01 · Lipids Health Dis · vol. 9 · issue 1 · p. 137
- Publisher
- BioMed Central
- Cited
- 28 citations · more than 77% of similar papers · 1.1× the field average
- References
- 57 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Fatty Acid Research and Health · Nuts composition and effects · Edible Oils Quality and Analysis
- Keywords
- Rapeseed, Food science, Polyunsaturated fatty acid, Lipidology, Cholesterol, Clinical chemistry, Blood lipids, Crossover study, Vegetable oil, Medicine, Chemistry, Animal science, Internal medicine, Biology, Biochemistry, Fatty acid
- MeSH
- arteries, humans, brassica napus, butter, fatty acids, omega-3, fatty acids, monounsaturated, lipoproteins, ldl, plant oils, diet, administration, oral, elasticity, adult, aged, middle aged, europe, male, cholesterol, ldl, cholesterol, hdl, metabolic syndrome, rapeseed oil
8 authors
From FI
- Ari PalomäkiKanta-Hämeen Keskussairaala
- Hanna Pohjantähti‐Maaroos · correspondingKuopio University Hospital; Kanta-Hämeen Keskussairaala
- Marja WalleniusKanta-Hämeen Keskussairaala
- Päivi KankkunenFinnish Institute of Occupational Health; Kanta-Hämeen Keskussairaala
- Heikki AroSitra; Finnish Medicines Agency Fimea; Agrifood Research Finland
- Sari HusgafvelKanta-Hämeen Keskussairaala
Abstract
Background
Rapeseed oil is the principal dietary source of monounsaturated and n-3 polyunsaturated fatty acids in the Northern Europe. However, the effect of rapeseed oil on the markers of subclinical atherosclerosis is not known. The purpose of this study was to compare the effects of dietary intake of cold-pressed turnip rapeseed oil (CPTRO) and butter on serum lipids, oxidized LDL and arterial elasticity in men with metabolic syndrome.
Methods
Thirty-seven men with metabolic syndrome completed an open and balanced crossover study. Treatment periods lasted for 6 to 8 weeks and they were separated from each other with an eight-week washout period. Subjects maintained their normal dietary habits and physical activity without major variations. The daily fat adjunct consisted either of 37.5 grams of butter or 35 mL of Virgino R CPTRO. Participants were asked to spread butter on bread on the butter period and to drink CPTRO on the oil period. The fat adjunct was used as such without heating or frying.
Results
Compared to butter, administration of CPTRO was followed by a reduction of total cholesterol by 8% (p < 0.001) and LDL cholesterol by 11% (p < 0.001). The level of oxidized LDL was 16% lower after oil period (p = 0.024). Minimal differences in arterial elasticity were not statistically significant.
Conclusion
Cold-pressed turnip rapeseed oil had favourable effects on circulating LDL cholesterol and oxidized LDL, which may be important in the management of patients at high cardiovascular risk.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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