Effects of hydroxytyrosol-enriched sunflower oil consumption on CVD risk factors
Vázquez-Velasco M, Esperanza Díaz L, Lucas R, Gómez-Martínez S, Bastida S, Marcos A, Sánchez-Muniz FJ
The British journal of nutrition · 31 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Randomized controlled trial (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Food provided by researchers
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2010-12-08 · Br J Nutr · vol. 105 · issue 10 · pp. 1448–1452
- Publisher
- Cambridge University Press
- Cited
- 46 citations · more than 72% of similar papers · 1.1× the field average
- References
- 25 works
- Access
- Free to read
- Research areas
- Antioxidant Activity and Oxidative Stress · Paraoxonase enzyme and polymorphisms · Fatty Acid Research and Health
- Keywords
- Hydroxytyrosol, Sunflower oil, Food science, Cholesterol, Chemistry, Biomarker, Phytosterol, Biochemistry, Antioxidant, Polyphenol
- MeSH
- humans, cardiovascular diseases, phenylethyl alcohol, cholesterol, plant oils, enzyme-linked immunosorbent assay, risk factors, cross-over studies, sunflower oil
7 authors
From ES
- Miguel Vázquez‐VelascoUniversidad Complutense de Madrid
- Ligia Esperanza DíazConsejo Superior de Investigaciones Científicas; Instituto de Ciencia y Tecnología de Alimentos y Nutrición
- Rocío LucasUniversidad Complutense de Madrid
- Sonia Gómez‐MartínezConsejo Superior de Investigaciones Científicas; Instituto de Ciencia y Tecnología de Alimentos y Nutrición
- Sara BastidaUniversidad Complutense de Madrid
- Ascensión MarcosConsejo Superior de Investigaciones Científicas; Instituto de Ciencia y Tecnología de Alimentos y Nutrición
Abstract
Inclusion of biophenols in traditional foods transforms them into functional foods that may help to decrease CVD risk. The aim of the present study was to determine whether the consumption of hydroxytyrosol-enriched sunflower oil (HSO) improves certain CVD biomarker values. A total of twenty-two healthy volunteers participated in a cross-over study involving two 3-week periods, separated by a 2-week washout period, in which volunteers consumed 800-1275 μg/d [corrected] of either HSO (45-50 mg/d of hydroxytyrosol) or non-enriched (control) sunflower oil. Total cholesterol, LDL-cholesterol, HDL-cholesterol, arylesterase activity, oxidised LDL and soluble vascular cell adhesion molecule (sVCAM-1) levels were measured in the plasma obtained at the beginning and at the end of each treatment period. The HSO group displayed a significantly higher level (P < 0·01) of arylesterase activity and significantly lower levels of oxidised LDL and sVCAM-1 (both P < 0·05) than the control group. These results suggest that HSO may help prevent CVD.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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