Central and peripheral fatigue during passive and exercise-induced hyperthermia
Périard JD, Caillaud C, Thompson MW
Medicine and science in sports and exercise · 42 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Randomized controlled trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2011-03-02 · Med Sci Sports Exerc · vol. 43 · issue 9 · pp. 1657–1665
- Publisher
- Lippincott Williams & Wilkins
- Cited
- 68 citations · more than 97% of similar papers · 6.5× the field average
- Impact
- Top 10% most cited in its field
- References
- 48 works
- Access
- Paywalled
- Research areas
- Exercise and Physiological Responses · Thermoregulation and physiological responses · Infrared Thermography in Medicine
- Keywords
- Isometric exercise, Hyperthermia, Peripheral, Turnover, Internal medicine, Heat stress, Medicine, Cardiology, Animal science, Biology
- MeSH
- humans, fever, exercise test, exercise, oxygen consumption, heart rate, muscle fatigue, isometric contraction, adult, male, quadriceps muscle, muscle strength
3 authors
From AU, QA
- Julien D. PériardThe University of Sydney; Qatar Airways (Qatar); Qatar Orthopaedic and Sports Medicine Hospital
- Corinne CaillaudThe University of Sydney
- Martin William ThompsonThe University of Sydney
Abstract
Purpose
Hyperthermia was induced during prolonged exercise (ExH) and passive heating (PaH) to isolate the influence of exercise on neuromuscular function during a maximal voluntary isometric contraction (MVC) of the quadriceps under heat stress. The influence of cardiovascular strain in limiting endurance performance in the heat was also examined.
Methods
On separate days, eight males cycled to exhaustion at 60% maximal oxygen uptake or were immersed in a water bath (∼41°C) until rectal temperature (Tre) increased to 39.5°C. The ExH and PaH interventions were performed in ambient conditions of 38°C and 60% relative humidity with Tre reaching 39.8°C during exercise. Before (control) and after each intervention, voluntary activation and force production capacity were evaluated by superimposing an electrically stimulated tetanus during a 45-s MVC.
Results
Force production decreased immediately after PaH and ExH compared with control, with the magnitude of decline being more pronounced after ExH (P < 0.01). Mean voluntary activation was also significantly depressed after both interventions (P < 0.01 vs control). However, the extent of decline in voluntary activation was maintained at ∼90% during both PaH and ExH MVC. This decline accounted for 41.5% (PaH) and 33.1% (ExH) of the decrease in force production. In addition, exhaustion coincided with a marked increase in HR (∼96% of maximum) and a decline in stroke volume (25%) and mean arterial pressure (10%) (P < 0.05).
Conclusions
The loss of force production capacity during hyperthermia originated from central and peripheral fatigue factors, with the combination of heat stress and previous contractile activity exacerbating the rate of decline. Thus, the observed significant rise in thermal strain in ExH and PaH impaired neuromuscular function and was associated with an exercise performance limiting increase in cardiovascular strain.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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