Study2011Open access

Effects of Music Listening on Cortisol Levels and Propofol Consumption during Spinal Anesthesia

Koelsch S, Fuermetz J, Sack U, Bauer K, Hohenadel M, Wiegel M, Kaisers UX, Heinke W

Frontiers in psychology · 76 citations

How it was studied

Design
Randomized controlled trial (classified by our AI screen)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Independent funding

Based on full-text disclosure statement.

Publication

Published
2011-01-01 · Front Psychol · vol. 2 · p. 58
Publisher
Frontiers Media
Cited
154 citations · more than 94% of similar papers · 4.6× the field average
Impact
Top 10% most cited in its field
References
76 works
Access
Open access (journal) · OTHER-OA
Research areas
Music Therapy and Health · Intensive Care Unit Cognitive Disorders · Pain Management and Placebo Effect
Keywords
Sedative, Propofol, Sedation, Psychology, Anesthesia, Placebo, Stimulus (psychology), Active listening, Medicine, Communication, Cognitive psychology

8 authors

From DE

  • Stefan Koelsch · correspondingFreie Universität Berlin
  • Julian FuermetzLeipzig University
  • Ulrich SackLeipzig University
  • Katrin I. BauerLeipzig University
  • Maximilian G. HohenadelLeipzig University
  • Martin WiegelLeipzig University

Abstract

Background

This study explores effects of instrumental music on the hormonal system (as indicated by serum cortisol and adrenocorticotropic hormone), the immune system (as indicated by immunoglobulin A) and sedative drug requirements during surgery (elective total hip joint replacement under spinal anesthesia with light sedation). This is the first study investigating this issue with a double-blind design using instrumental music.

Methodology/principal findings

Patients (n = 40) were randomly assigned either to a music group (listening to instrumental music), or to a control group (listening to a non-musical placebo stimulus). Both groups listened to the auditory stimulus about 2 h before, and during the entire intra-operative period (during the intra-operative light sedation, subjects were able to respond lethargically to verbal commands). Results indicate that, during surgery, patients of the music group had a lower propofol consumption, and lower cortisol levels, compared to the control group.

Conclusion/significance

Our data show that listening to music during surgery under regional anesthesia has effects on cortisol levels (reflecting stress-reducing effects) and reduces sedative requirements to reach light sedation.

Abstract via Europe PMC. Copyright remains with the authors or publisher.

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