Cruciferous vegetables intake and risk of prostate cancer: a meta-analysis
Liu B, Mao Q, Cao M, Xie L
International journal of urology : official journal of the Japanese Urological Association · 102 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Not stated
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2011-11-28 · Int J Urol · vol. 19 · issue 2 · pp. 134–141
- Publisher
- Wiley
- Cited
- 145 citations · more than 93% of similar papers · 3.3× the field average
- Impact
- Top 10% most cited in its field
- References
- 34 works
- Access
- Paywalled
- Research areas
- Genomics, phytochemicals, and oxidative stress · Antioxidant Activity and Oxidative Stress · Glutathione Transferases and Polymorphisms
- Keywords
- Cruciferous vegetables, Medicine, Confidence interval, Prostate cancer, Relative risk, Cohort study, Meta-analysis, Cancer, Publication bias, Population, Cohort, Internal medicine, Gynecology, Oncology, Environmental health
- MeSH
- humans, brassicaceae, vegetables, prostatic neoplasms, incidence, risk assessment, feeding behavior, male, global health, surveys and questionnaires
4 authors
From CN
- Ben LiuZhejiang University
- Qiqi Mao · correspondingZhejiang University
- Min CaoZhejiang University
- Liping XieZhejiang University
Abstract
Objective
To evaluate the relationship between cruciferous vegetables intake and risk of prostate cancer.
Methods
A systematic literature search up to June 2011 was carried out in PubMed, and the references of retrieved articles were screened. The summary relative risks with 95% confidence interval for the highest versus the lowest intake of cruciferous vegetables were calculated. Heterogeneity and publication bias were also evaluated.
Results
Seven cohort and six population-based case-control studies met the inclusion criteria of the meta-analysis. A significantly decreased prostate cancer risk was observed overall in the cruciferous vegetables intake group (relative risks = 0.90; 95% confidence interval 0.85-0.96) and the subgroup of case-control studies (relative risks = 0.79; 95% confidence interval 0.69-0.89), but not in cohort studies (relative risks = 0.95; 95% confidence interval 0.88-1.02). No heterogeneity and publication bias were detected across studies.
Conclusion
Cruciferous vegetables intake is related to the decreased risk of prostate cancer. Because of the limited number of studies, further prospective studies are needed to explore the protective effect of cruciferous vegetables on prostate cancer.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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