Randomized controlled trial2012

Effect of adjunctive low level laser therapy (LLLT) on nonsurgical treatment of chronic periodontitis

Makhlouf M, Dahaba MM, Tunér J, Eissa SA, Harhash TA

Photomedicine and laser surgery · 56 citations

Review labels

Funding not disclosed

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Randomized controlled trial (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Funding not disclosed

Publication

Published
2012-01-10 · Photomed Laser Surg · vol. 30 · issue 3 · pp. 160–166
Publisher
Mary Ann Liebert, Inc.
Cited
81 citations · more than 93% of similar papers · 3.9× the field average
Impact
Top 10% most cited in its field
References
15 works
Access
Paywalled
Research areas
Laser Applications in Dentistry and Medicine · Oral microbiology and periodontitis research · Endodontics and Root Canal Treatments
Keywords
Medicine, Scaling and root planing, Chronic periodontitis, Low level laser therapy, Dentistry, Quadrant (abdomen), Randomized controlled trial, Periodontitis, Laser therapy, Surgery, Laser
MeSH
humans, radiography, treatment outcome, dental plaque index, periodontal index, follow-up studies, double-blind method, radiation dosage, dental scaling, root planing, dose-response relationship, radiation, bone density, time factors, reference values, adult, middle aged, female, male, chronic periodontitis, young adult, low-level light therapy

5 authors

From US, EG

  • M Vincent Makhlouf · correspondingLaser Institute of America
  • Mushira Mohamed DahabaCairo University
  • Jan Tunér
  • Sohair A. EissaCairo University
  • Tarek Abdel Hamid HarhashCairo University

Abstract

Objective

The aim of this split-mouth, double blinded, short-term, controlled clinical trial was to study the effect of low-level laser therapy (LLLT) as an adjunct to scaling and root planing (SRP) for treatment of chronic periodontitis.

Background data

LLLT is reported to improve the outcome of traditional SRP, but the evidence is still weak.

Materials and methods

Sixteen patients with a probing pocket depth (PPD) of 4-6 mm involving at least three teeth in each quadrant were recruited for the study. Afterwards, SRP quadrants were randomly assigned for 10 sessions of LLLT.

Results

Results showed that when compared to sites treated with SRP alone, those treated with SRP+LLLT (10 sessions, 830 nm, 100 mW, 3 J per point, 3 J/cm(2)) exhibited greater reductions in PPD at 5 weeks and 3 months but not at 6 months. Further, SRP+LLLT-treated sites had a statistically significant increase in mean radiographic bone density when comparing 6- and 12-month data and overall from baseline to 12 months. There was a trend to reduce interleukin (IL)-1β but the difference between control and laser sites was not statistically significant.

Conclusions

SRP combined with LLLT improved radiographic bone density and short-term PPD reduction in patients with chronic periodontitis, but did not significantly affect either the gingival crevicular fluid of IL-1β or the gingival or plaque index.

Abstract via Europe PMC. Copyright remains with the authors or publisher.

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