Case-control study2012

Egg consumption and the risk of type 2 diabetes mellitus: a case-control study

Radzevičienė L, Ostrauskas R

Public health nutrition · 31 citations

Review labels

Food frequency questionnaireFunding not disclosed

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Case-control study (indexed by PubMed)
Studied in
People
Main outcome
Clinical events such as disease or death
Intake measured by
Food frequency questionnaire

Who paid for it

Funding
Funding not disclosed

Publication

Published
2012-03-06 · Public Health Nutr · vol. 15 · issue 8 · pp. 1437–1441
Publisher
Cambridge University Press
Cited
45 citations · more than 94% of similar papers · 4.6× the field average
Impact
Top 10% most cited in its field
References
29 works
Access
Free to read
Research areas
Nutritional Studies and Diet · Diet and metabolism studies · Consumer Attitudes and Food Labeling
Keywords
Medicine, Diabetes mellitus, Odds ratio, Type 2 Diabetes Mellitus, Confounding, Internal medicine, Logistic regression, Confidence interval, Case-control study, Type 2 diabetes, Endocrinology
MeSH
humans, diabetes mellitus, type 2, triglycerides, body mass index, diet, multivariate analysis, confidence intervals, logistic models, odds ratio, risk factors, case-control studies, smoking, motor activity, eggs, adult, aged, middle aged, outpatients, lithuania, female, male, surveys and questionnaires

2 authors

From LT

  • Lina Radzevičienė · correspondingLithuanian University of Health Sciences
  • Rytas OstrauskasLithuanian University of Health Sciences

Abstract

Objective

Type 2 diabetes mellitus appears to involve an interaction between susceptible genetic backgrounds and environmental factors including highly calorific diets. As it is important to identify modifiable risk factors that may help reduce the risk of type 2 diabetes mellitus, the aim of the present study was to determine the association between egg consumption and the risk of type 2 diabetes mellitus.

Design

A specifically designed questionnaire was used to collect information on possible risk factors of type 2 diabetes mellitus. The odds ratios and 95 % confidence intervals for type 2 diabetes mellitus were calculated by conditional logistic regression.

Setting

A case-control study in a Lithuanian out-patient clinic was performed in 2001.

Subjects

A total of 234 cases with a newly confirmed diagnosis of type 2 diabetes mellitus and 468 controls free of the disease.

Results

Variables such as BMI, family history of diabetes, cigarette smoking, education, morning exercise and plasma TAG level were retained in multivariate logistic regression models as confounders because their inclusion changed the value of the odds ratio by more than 10 % in any exposure category. After adjustment for possible confounders more than twofold increased risk of type 2 diabetes mellitus was determined for individuals consuming 3-4·9 eggs/week (OR = 2·60; 95 % CI 1·34, 5·08) and threefold increased risk of the disease was determined for individuals consuming ≥5 eggs/week (OR = 3·02; 95 % CI 1·14, 7·98) compared with those eating <1 egg/week.

Conclusions

Our data support a possible relationship of egg consumption and increased risk of type 2 diabetes mellitus.

Abstract via Europe PMC. Copyright remains with the authors or publisher.

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