Effects of pistachios on body weight in Chinese subjects with metabolic syndrome
Wang X, Li Z, Liu Y, Lv X, Yang W
Nutrition journal · 63 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Randomized controlled trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Food provided by researchers
Who paid for it
- Funding
- Industry funded
- Authors
- At least one author declares a financial tie to industry
Based on full-text disclosure statement.
Publication
- Published
- 2012-04-03 · Nutr J · vol. 11 · issue 1 · p. 20
- Publisher
- BioMed Central
- Cited
- 85 citations · more than 95% of similar papers · 4.9× the field average
- Impact
- Top 10% most cited in its field
- References
- 23 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Nuts composition and effects · Food composition and properties · Peanut Plant Research Studies
- Keywords
- Medicine, Metabolic syndrome, Internal medicine, Clinical nutrition, Blood pressure, Diabetes mellitus, Lipid profile, Waist, Blood lipids, Outpatient clinic, Body mass index, Endocrinology, Physical therapy, Obesity, Cholesterol
- MeSH
- liver, humans, pistacia, nuts, weight gain, insulin, blood glucose, lipids, waist-hip ratio, risk factors, blood pressure, postprandial period, adult, aged, middle aged, china, female, male, metabolic syndrome, asian people
5 authors
From CN, US
- Xin WangChina-Japan Friendship Hospital
- Zhaoping LiUniversity of California, Los Angeles
- Yanjun LiuPLA 306 Hospital
- Xiaofeng LvThe Military General Hospital of Beijing PLA
- Wenying Yang · correspondingChina-Japan Friendship Hospital
Abstract
Background
Studies have shown that pistachios can improve blood lipid profiles in subjects with moderate hypercholesterolemia which could reduce the risk of cardiovascular disease. However, there is also a widely perceived view that eating nuts can lead to body weight gain due to their high fat content.
Purpose
To investigate the impact of different dosages of pistachios on body weight, blood pressure, blood lipids, blood glucose and insulin in subjects with metabolic syndrome.
Methods
Ninety subjects with metabolic syndrome (consistent with 2005 International Diabetes Federation metabolic syndrome standard without diabetes) were enrolled in three endocrinology outpatient clinics in Beijing. All subjects received dietary counseling according to the guidelines of the American Heart Association Step I diet. After a 4 week run-in, subjects were randomized to consume either the recommended daily serving of 42 g pistachios (RSG), a higher daily serving of 70 g pistachio (HSG) or no pistachios (DCG) for 12 weeks.
Results
Subjects in all three groups were matched at baseline for BMI: DCG 28.03 ± 4.3; RSG 28.12 ± 3.22; and HSG 28.01 ± 4.51 kg/m2. There were no significant changes in body weight or BMI in any groups during the study nor any change from baseline at any time point in any group. During the entire study, there were no significant differences in waist-to-hip ratio among the groups or any change from baseline in any group (DCG -0.00 ± 0.03, RSG -0.01 ± 0.02 and HSG 0.01 ± 0.04). There were no significant differences detected among groups in triglycerides, fasting glucose and 2 hour postprandial glucose following a 75 gram glucose challenge. Exploratory analyses demonstrated that glucose values 2 h after a 75 gm glucose challenge were significantly lower at week 12 compared with baseline values in the HSG group (-1.13 ± 2.58 mmol/L, p = 0.02), and a similar trend was noted in the RSG group (-0.77 ± 2.07 mmol/L, p = 0.06), while no significant change was seen in the DCG group (-0.15 ± 2.27 mmol/L, p = 0.530). At the end of study, serum triglyceride levels were significantly lower compared with baseline in the RSG group (-0.38 ± 0.79 mmol/L, p = 0.018), but no significant changes were observed in the HSG or DCG groups.
Conclusion
Despite concerns that pistachio nut consumption may promote weight gain, the daily ingestion of either 42 g or 70 g of pistachios for 12 weeks did not lead to weight gain or an increase in waist-to-hip ratio in Chinese subjects with metabolic syndrome. In addition, pistachio consumption may improve the risk factor associated with the metabolic syndrome.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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