Congenital amusia persists in the developing brain after daily music listening
Mignault Goulet G, Moreau P, Robitaille N, Peretz I
PloS one · 38 citations
How it was studied
- Design
- Case-control study (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- Government
- Canadian Institutes of Health Research
- Government
- Natural Sciences and Engineering Research Council of Canada
Based on 2 listed funder(s).
Publication
- Published
- 2012-05-11 · PLoS One · vol. 7 · issue 5 · p. e36860
- Publisher
- Public Library of Science
- Cited
- 57 citations · more than 93% of similar papers · 3.4× the field average
- Impact
- Top 10% most cited in its field
- References
- 52 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Neuroscience and Music Perception · Multisensory perception and integration · Hearing Loss and Rehabilitation
- Keywords
- N100, Psychology, Mismatch negativity, Audiology, Neuroscience, Auditory cortex, Context (archaeology), Population, Cognition, Developmental psychology, Medicine, Event-related potential, Electroencephalography, Biology
- MeSH
- auditory cortex, auditory pathways, humans, auditory perceptual disorders, music therapy, case-control studies, auditory perception, pitch perception, pitch discrimination, evoked potentials, auditory, child, female, male
4 authors
From CA
- Geneviève Mignault GouletInternational Laboratory for Brain, Music and Sound Research; Université de Montréal
- Patricia MoreauInternational Laboratory for Brain, Music and Sound Research; Université de Montréal
- Nicolas RobitailleInternational Laboratory for Brain, Music and Sound Research; Université de Montréal
- Isabelle Peretz · correspondingInternational Laboratory for Brain, Music and Sound Research; Université de Montréal
Abstract
Congenital amusia is a neurodevelopmental disorder that affects about 3% of the adult population. Adults experiencing this musical disorder in the absence of macroscopically visible brain injury are described as cases of congenital amusia under the assumption that the musical deficits have been present from birth. Here, we show that this disorder can be expressed in the developing brain. We found that (10-13 year-old) children exhibit a marked deficit in the detection of fine-grained pitch differences in both musical and acoustical context in comparison to their normally developing peers comparable in age and general intelligence. This behavioral deficit could be traced down to their abnormal P300 brain responses to the detection of subtle pitch changes. The altered pattern of electrical activity does not seem to arise from an anomalous functioning of the auditory cortex, because all early components of the brain potentials, the N100, the MMN, and the P200 appear normal. Rather, the brain and behavioral measures point to disrupted information propagation from the auditory cortex to other cortical regions. Furthermore, the behavioral and neural manifestations of the disorder remained unchanged after 4 weeks of daily musical listening. These results show that congenital amusia can be detected in childhood despite regular musical exposure and normal intellectual functioning.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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