Processed meat consumption and risk of cancer: a multisite case-control study in Uruguay
De Stefani E, Boffetta P, Ronco AL, Deneo-Pellegrini H, Correa P, Acosta G, Mendilaharsu M, Luaces ME, Silva C
British journal of cancer · 28 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Case-control study (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Not stated
Who paid for it
- Funding
- Independent funding
- University or hospital
- Centre International de Recherche sur le Cancer
Based on 1 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2012-09-25 · Br J Cancer · vol. 107 · issue 9 · pp. 1584–1588
- Publisher
- Springer Nature
- Cited
- 41 citations · more than 96% of similar papers · 5.6× the field average
- Impact
- Top 10% most cited in its field
- References
- 25 works
- Access
- Open access (hybrid journal) · CC-BY-NC-SA
- Research areas
- Nutritional Studies and Diet · Agriculture Sustainability and Environmental Impact · Consumer Attitudes and Food Labeling
- Keywords
- Medicine, Rectum, Stomach, Processed meat, Case-control study, Odds ratio, Carcinoma, Colorectal cancer, Lung, Renal cell carcinoma, Internal medicine, Cancer, Larynx, Prostate, Gastroenterology, Kidney cancer, Urinary bladder, Etiology, Surgery, Biology, Food science
- MeSH
- humans, neoplasms, risk factors, case-control studies, life style, meat products, uruguay, female, male, interviews as topic, surveys and questionnaires
9 authors
From UY, US
- E De Stéfani · correspondingUniversidad de la República de Uruguay; Universidad de Montevideo
- Paolo BoffettaIcahn School of Medicine at Mount Sinai
- Álvaro L. RoncoUniversidad CLAEH
- Hugo Deneo‐PellegriniUniversidad de la República de Uruguay; Universidad de Montevideo
- P CorréaVanderbilt University Medical Center
- Giselle AcostaUniversidad de la República de Uruguay; Universidad de Montevideo
Abstract
Background
The role of processed meat in the aetiology of several cancers was explored in detail.
Methods
In the time period 1996-2004, a multisite case-control study was conducted in Montevideo, Uruguay. The study included 6 060 participants (3 528 cases and 2 532 controls) corresponding to cancers of the oral cavity, pharynx, oesophagus, stomach, colon, rectum, larynx, lung, female breast, prostate, urinary bladder, and kidney (renal cell carcinoma only).
Results
The highest odds ratios (ORs) were positively associated with cancers of the colon, rectum, stomach, oesophagus, and lung. With the exception of renal cell carcinoma, the remaining cancer sites were significantly associated with elevated risks for processed meat consumption. Furthermore, mortadella, salami, hot dog, ham, and salted meat were strongly associated with risk of several cancer sites.
Conclusion
It could be concluded that processed meat intake could be a powerful multiorgan carcinogen.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY-NC-SA).
Community trust
Loading…
How much do you trust this study's findings?
Comments
Sign in to rate, comment on or flag this study.Sign inSomething wrong here?
Flag this study if its information, labels or funding look wrong. An editor reviews every flag.
Sign in to rate, comment on or flag this study.Sign inEducational information about published research. Not medical advice, and not a recommendation to start or stop anything.