Effects of thermal stress on the activity of selected lysosomal enzymes in blood of experienced and novice winter swimmers
Mila-Kierzenkowska C, Woźniak A, Szpinda M, Boraczyński T, Woźniak B, Rajewski P, Sutkowy P
Scandinavian journal of clinical and laboratory investigation · 17 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Controlled clinical trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Mechanisms only
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2012-10-15 · Scand J Clin Lab Invest · vol. 72 · issue 8 · pp. 635–641
- Publisher
- Taylor & Francis
- Cited
- 21 citations · more than 85% of similar papers · 2.1× the field average
- References
- 29 works
- Access
- Paywalled
- Research areas
- Exercise and Physiological Responses · Muscle and Compartmental Disorders · Autophagy in Disease and Therapy
- Keywords
- Acid phosphatase, Cathepsin D, Enzyme, Enzyme assay, Chemistry, Lysosome, Cathepsin, Protease, Internal medicine, Endocrinology, Biochemistry, Medicine
- MeSH
- lysosomes, humans, enzymes, temperature, seasons, swimming, adult, male, stress, physiological
7 authors
From PL
- Celestyna Mila-Kierzenkowska · correspondingNicolaus Copernicus University
- Alina WoźniakNicolaus Copernicus University
- Michał SzpindaNicolaus Copernicus University
- Tomasz BoraczyńskiOlsztyńska Szkoła Wyższa im. Józefa Rusieckiego
- Bartosz WoźniakStanisław Staszic University of Applied Sciences in Piła
- Paweł RajewskiUniversity of Bydgoszcz
Abstract
Background
The aim of this study was to determine the effects of exposure to cold and heat on the activity of selected lysosomal enzymes as well as on the activity of the protease inhibitor, which are all considered to be markers of cellular damage.
Material
Two groups of healthy volunteers were included in the study. The first group consisted of experienced winter swimmers who practiced bathing in ice-cold water once a week, while the other group was comprised of persons who had never taken part in winter swimming before. During the experiment all the participants bathed in a river with a water temperature of 0 °C. The same volunteers were later subjected to a sauna bath at an air temperature of 85 °C.
Methods
The activity of cathepsin D, alpha-1-antitrypsin, arylsulphatase and acid phosphatase was measured in the participant's blood serum.
Results
After exposure to cold water no changes in the parameters studied could be found. However, after the sauna an increase in the activity of arylsulphatase and alfa-1-antitrypsin accompanied by a decrease of cathepsin D activity could be observed.
Conclusions
Winter swimming seems to have no effect on the activity of the lysosomal enzymes. By contrast, an increase of certain lysosomal enzymes after the sauna suggests that it may be deleterious to the lysosomal membranes. Furthermore it seems that regular winter swimming combined with sauna, according to hormesis theory, induces some adaptive response.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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