Egg intake improves carotenoid status by increasing plasma HDL cholesterol in adults with metabolic syndrome
Blesso CN, Andersen CJ, Bolling BW, Fernandez ML
Food & function · 58 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Randomized controlled trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Food provided by researchers
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2012-10-29 · Food Funct · vol. 4 · issue 2 · pp. 213–221
- Publisher
- Royal Society of Chemistry
- Cited
- 81 citations · more than 86% of similar papers · 2.2× the field average
- References
- 45 works
- Access
- Paywalled
- Research areas
- Antioxidant Activity and Oxidative Stress · Obesity, Physical Activity, Diet · Adipokines, Inflammation, and Metabolic Diseases
- Keywords
- Zeaxanthin, Lutein, Yolk, Carotenoid, Internal medicine, Endocrinology, Population, Lipoprotein, Cholesterol, Biology, Lycopene, Food science, Medicine
- MeSH
- animals, chickens, humans, carotenoids, beta carotene, xanthophylls, lutein, eggs, adult, aged, middle aged, female, male, cholesterol, hdl, zeaxanthins, metabolic syndrome
4 authors
From US
- Christopher N. BlessoUniversity of Connecticut
- Catherine J. AndersenUniversity of Connecticut
- Bradley W. BollingUniversity of Connecticut
- María Luz Fernández · correspondingUniversity of Connecticut
Abstract
Metabolic syndrome (MetS) is associated with reductions in plasma lutein and zeaxanthin, along with altered composition of their lipoprotein transporters which may affect disease risk. Egg yolk intake has been demonstrated to increase plasma lutein and zeaxanthin in other populations. The objective of this study was to investigate the effects of whole egg feeding on plasma and lipoprotein carotenoids in participants with MetS. Participants consumed 3 whole eggs per day (EGG, n = 20) or the equivalent amount of yolk-free egg substitute (SUB, n = 17), as part of a carbohydrate-restricted diet (CRD) for 12 weeks. Post-intervention, the EGG group had significant increases in plasma lutein (+21%), zeaxanthin (+48%), and β-carotene (+24%), while the SUB group had increases in plasma β-carotene (+55%) only. Significant enrichment of isolated HDL and LDL fractions in lutein (+20% HDL, +9% LDL) and zeaxanthin (+57% HDL, +46% LDL) was observed in the EGG group after 12 weeks. Increases in the proportion of plasma carotenoids carried by HDL was seen for lutein (P < 0.01), zeaxanthin (P < 0.01), β-cryptoxanthin (P < 0.05), and lycopene (P < 0.05) for all participants after the 12 week intervention. Daily intake of 3 whole eggs, as part of a CRD, increased both plasma and lipoprotein lutein and zeaxanthin. Egg yolk may represent an important food source to improve plasma carotenoid status in a population at high risk for cardiovascular disease and type 2 diabetes.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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