Whole grain, dietary fiber, and incidence of endometrial cancer in a Danish cohort study
Aarestrup J, Kyrø C, Christensen J, Kristensen M, Würtz AM, Johnsen NF, Overvad K, Tjønneland A, Olsen A
Nutrition and cancer · 20 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cohort study (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Food frequency questionnaire
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2012-11-01 · Nutr Cancer · vol. 64 · issue 8 · pp. 1160–1168
- Publisher
- Routledge
- Cited
- 33 citations · more than 77% of similar papers · 1.1× the field average
- References
- 47 works
- Access
- Paywalled
- Research areas
- Cancer Risks and Factors · Phytoestrogen effects and research · Nutrition and Health in Aging
- Keywords
- Medicine, Endometrial cancer, Incidence (geometry), Cohort, Proportional hazards model, Cohort study, Cancer, Whole grains, Internal medicine, Gynecology, Biology, Food science
- MeSH
- adipose tissue, humans, endometrial neoplasms, gonadal steroid hormones, body mass index, estrogen replacement therapy, diet, cohort studies, prospective studies, life style, menopause, bread, dietary fiber, middle aged, denmark, female, surveys and questionnaires, edible grain, secale
9 authors
From DK
- Julie AarestrupDanish Cancer Society
- Cecilie KyrøDanish Cancer Society
- Jane ChristensenDanish Cancer Society
- Mette KristensenUniversity of Copenhagen
- Anne Mette Lund WürtzDanish Cancer Society
- Nina Føns JohnsenDanish Cancer Society
Abstract
Whole grains and dietary fiber might be inversely associated with endometrial cancer risk through their effects on sex hormone metabolism and body fat. We investigated whether a higher intake of whole grains and dietary fiber was associated with a lower incidence of endometrial cancer in the Diet, Cancer and Health cohort of 29,875 women aged 50-64 years at enrollment in 1993-1997. Information on diet and lifestyle was derived from self-administered questionnaires. The incidence rate ratios and 95% confidence intervals were estimated based on a Cox proportional hazards model. Of the 24,418 women included as cohort members, 217 had a diagnosis of endometrial cancer. No clear associations were found between intake of whole grains or dietary fiber and the incidence of endometrial cancer.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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