Egg intake and bladder cancer risk: A meta-analysis
Fang D, Tan F, Wang C, Zhu X, Xie L
Experimental and therapeutic medicine · 8 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Meta-analysis (classified by our AI screen)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Not stated
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2012-08-16 · Exp Ther Med · vol. 4 · issue 5 · pp. 906–912
- Publisher
- Spandidos Publishing
- Cited
- 13 citations · more than 40% of similar papers · 0.2× the field average
- References
- 33 works
- Access
- Open access (free to publish)
- Research areas
- Nutritional Studies and Diet · Bladder and Urothelial Cancer Treatments · Phytoestrogen effects and research
- Keywords
- Bladder cancer, Meta-analysis, Cancer, Medicine, Epidemiology, Cohort study, Incidence (geometry), Oncology, Internal medicine, Cohort, Physiology
5 authors
From CN
- Danbo FangFirst Affiliated Hospital Zhejiang University; Zhejiang University
- Fu-Qing TanZhejiang University
- Chaojun WangZhejiang University
- Xuan-Wen ZhuZhejiang University
- Liping XieZhejiang University
Abstract
Egg intake has been hypothesized to promote carcinogenesis due to its potential to increase circulating levels of cholesterol. Epidemiological findings regarding the association between egg consumption and risk of bladder cancer have been inconsistent. We performed a meta-analysis of the available data. Relevant studies were identified by a PubMed database search of articles dating from between January 1980 and December 2011. We identified 4 cohort and 9 case-control studies of egg intake and risk of bladder cancer. Both fixed- and random-effects models were used to calculate the summary risk estimates (REs). The combined RE of bladder cancer for the highest compared with the lowest egg intake was 0.94 (95% CI, 0.69-1.18) and weak evidence of heterogeneity was observed. The association between egg intake and risk of bladder cancer differed significantly by geographic region, with a 28% reduced risk in Japanese. Our results provided no strong evidence of a significant association of egg consumption with bladder cancer incidence but showed a protective effect in Japanese.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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