Cross-sectional assessment of nut consumption and obesity, metabolic syndrome and other cardiometabolic risk factors: the PREDIMED study
Ibarrola-Jurado N, Bulló M, Guasch-Ferré M, Ros E, Martínez-González MA, Corella D, Fiol M, Wärnberg J, Estruch R, Román P, Arós F, Vinyoles E, Serra-Majem L, Pintó X, Covas MI, Basora J, Salas-Salvadó J, PREDIMED Study Investigators
PloS one · 79 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cross-sectional study (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Food frequency questionnaire
Who paid for it
- Funding
- Independent funding
- University or hospital
- Universitat de València
- University or hospital
- Universidad de Navarra
- University or hospital
- Universitat de Barcelona
- University or hospital
- Universitat Rovira i Virgili
- University or hospital
- Institut d'Estudis Catalans
- Government
- Instituto de Salud Carlos III
- Government
- European Regional Development Fund
- Grants
- Instituto de Salud Carlos III (RD06/0045); Instituto de Salud Carlos III (G03/140); European Regional Development Fund ((RD 06/0045); Universidad de Navarra (G03/140); European Regional Development Fund (G03/140); Instituto de Salud Carlos III (PI1001407)
Based on 7 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2013-02-27 · PLoS One · vol. 8 · issue 2 · p. e57367
- Publisher
- Public Library of Science
- Cited
- 115 citations · more than 99% of similar papers · 8.5× the field average
- Impact
- Top 10% most cited in its field
- References
- 44 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Nuts composition and effects · Peanut Plant Research Studies · Botany, Ecology, and Taxonomy Studies
- Keywords
- Medicine, Dyslipidemia, Metabolic syndrome, Odds ratio, Abdominal obesity, Obesity, Diabetes mellitus, Internal medicine, Cross-sectional study, Confounding, Confidence interval, Population, Epidemiology, Body mass index, Environmental health, Endocrinology, Pathology
- MeSH
- humans, nuts, cardiovascular diseases, obesity, prevalence, multivariate analysis, confidence intervals, odds ratio, risk factors, cross-sectional studies, feeding behavior, aged, aged, 80 and over, middle aged, mediterranean region, female, male, metabolic syndrome
18 authors
From ES
- Núria Ibarrola-Jurado · correspondingInstituto de Salud Carlos III; Institut de Recerca Biomèdica Catalunya Sud; Universitat Rovira i Virgili
- Mònica Bulló · correspondingInstituto de Salud Carlos III; Institut de Recerca Biomèdica Catalunya Sud; Universitat Rovira i Virgili
- Marta Liu Guasch-Ferré · correspondingInstituto de Salud Carlos III; Institut de Recerca Biomèdica Catalunya Sud; Universitat Rovira i Virgili
- Emilio Peña Ros · correspondingInstituto de Salud Carlos III; Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
- Miguel Ángel Martínez‐González · correspondingUniversidad de Navarra
- Dolores Corella · correspondingUniversitat de València; Instituto de Salud Carlos III
Abstract
Introduction
Prospective studies have consistently suggested that nut consumption is inversely related to fatal and non-fatal coronary heart disease. Limited data are available on the epidemiological associations between nut intake and cardiometabolic risk factors.
Objective
To evaluate associations between frequency of nut consumption and prevalence of cardiometabolic risk factors [obesity, metabolic syndrome (MetS), type-2 diabetes, hypertension, and dyslipidemia] in a Mediterranean population at high cardiovascular risk.
Materials and methods
Cross-sectional study of 7,210 men and women (mean age, 67 y) recruited into the PREDIMED study. MetS was defined by the harmonized ATPIII and IDF criteria. Diabetes and hypertension were assessed by clinical diagnosis and dyslipidemia (high triglycerides, low HDL-cholesterol, and hypercholesterolemia) by lipid analyses. Nut consumption was assessed using a validated food frequency questionnaire and categorized as 3 servings/wk. Control of confounding was done with multivariate logistic regression.
Results
Compared to participants consuming 3 servings/wk had lower adjusted odds ratios (OR) for obesity (0.61, 95% confidence interval 0.54 to 0.68; P-trend <0.001), MetS (0.74, 0.65 to 0.85; P-trend<0.001), and diabetes (0.87, 0.78 to 0.99; P-trend = 0.043). Higher nut consumption was also associated with lower risk of the abdominal obesity MetS criterion (OR 0.68, 0.60 to 0.79; P-trend<0.001). No significant associations were observed for the MetS components high blood pressure, dyslipidemia, or elevated fasting glucose.
Conclusions
Nut consumption was inversely associated with the prevalence of general obesity, central obesity, MetS, and diabetes in subjects at high cardiovascular risk.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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