Evaluation of the effect of low level laser on prevention of chemotherapy-induced mucositis
Arbabi-Kalati F, Arbabi-Kalati F, Moridi T
Acta medica Iranica · 36 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Randomized controlled trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2013-04-06 · Acta Med Iran · vol. 51 · issue 3 · pp. 157–62
- Publisher
- National Institutes of Health
- Cited
- 53 citations · more than 93% of similar papers · 3.3× the field average
- Impact
- Top 10% most cited in its field
- References
- 22 works
- Access
- Open access (repository copy) · CC-BY-SA
- Research areas
- Oral health in cancer treatment · Head and Neck Cancer Studies · Cancer Diagnosis and Treatment
- Keywords
- Mucositis, Medicine, Chemotherapy, Radiation therapy, Low level laser therapy, Complication, Internal medicine, Surgery, Laser therapy, Laser
- MeSH
- humans, head and neck neoplasms, xerostomia, stomatitis, pain, treatment outcome, cohort studies, double-blind method, adolescent, adult, aged, middle aged, female, male, young adult, low-level light therapy
3 authors
From IR
- Farshid Arbabi-KalatiTehran University of Medical Sciences
- Fateme Arbabi‐Kalati
- Tahora Moridi
Abstract
Radiotherapy in the head and neck region and chemotherapy might give rise to oral mucositis which is a severe and painful inflammation. There is no known definite cure for mucositis. A number of studies have attempted to evaluate the effect of low-power laser on radiotherapy- and chemotherapy-induced mucositis. The present study was undertaken to evaluate the effect of low-power laser on the prevention of mucositis, xerostomia and pain as a result of chemotherapy. The subjects in this double-blind randomized controlled study were 24 adult patients who underwent chemotherapy during 2009-2010. The results showed that low-power laser was able to decrease the effect of chemotherapy on oral mucositis, xerostomia and pain in a variety of malignancies (P<0.05). It can be concluded that low-power laser might decrease the intensity of mucositis.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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