Egg consumption and risk of bladder cancer: a meta-analysis
Li F, Zhou Y, Hu RT, Hou LN, Du YJ, Zhang XJ, Olkkonen VM, Tan WL
Nutrition and cancer · 19 citations
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Not stated
Who paid for it
- Funding
- Independent funding
- Government
- Natural Science Foundation of Guangdong Province
Based on 1 listed funder(s).
Publication
- Published
- 2013-05-01 · Nutr Cancer · vol. 65 · issue 4 · pp. 538–546
- Publisher
- Routledge
- Cited
- 21 citations · more than 51% of similar papers · 0.5× the field average
- References
- 31 works
- Access
- Paywalled
- Research areas
- Nutritional Studies and Diet · Bladder and Urothelial Cancer Treatments · Nutrition, Health and Food Behavior
- Keywords
- Bladder cancer, Meta-analysis, Consumption (sociology), Medicine, Environmental health, Oncology, Cancer, Internal medicine, Urology
- MeSH
- humans, diet, case-control studies, cohort studies, eggs, urinary bladder neoplasms, cooking
8 authors
From CN, FI
- Fei Ran LiNanfang Hospital; Southern Medical University
- You ZhouMinerva Foundation
- Ruiting HuThe People's Hospital of Guangxi Zhuang Autonomous Region; Riverside Hospital of Guangxi Zhuang Autonomous Region
- Lina HouNanfang Hospital; Southern Medical University
- Yuejun DuNanfang Hospital; Southern Medical University
- Xinji ZhangThe First People's Hospital of Shunde; Southern Medical University
Abstract
The findings of epidemiologic studies on the association between egg consumption and bladder cancer risk remain conflicting. We conducted a meta-analysis to clarify the potential association between egg consumption and bladder cancer risk. Four cohort studies and 9 case-control studies in the PubMed database through February 2012 were identified on egg consumption and risk of bladder cancer involving 2715 cases and 184,727 participants. Random-effects models were used to calculate the summary relative risk estimates (SRRE) based on the highest compared with the lowest category of egg consumption. In addition, we performed stratified analyses and sensitivity and dose-response analyses to examine the association. Overall, no significant association was observed between egg consumption and bladder cancer (SRRE = 1.11 95% CI: 0.90-1.35). However, increased risk of bladder cancer was detected in North/South America (SRRE = 1.40 95% CI: 1.05-1.86) and, moreover, fried egg intake positively associated with bladder cancer as well (SRRE = 2.04, 95% CI: 1.41-2.95). In conclusion, our findings suggest no significant association between egg consumption and bladder cancer risk, except for a possible positive relationship with the intake of fried eggs based on the limited number of studies. Additional studies, especially large prospective cohort studies, are warranted to confirm these findings.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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