Red meat snacks for chronic hemodialysis patients: effect on inflammatory activity (a pilot study)
Maduro IP, Nonino CB, Sakamoto LM, Meirelles MG, Cardeal Da Costa JA, Marchini JS
Renal failure · 7 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Controlled clinical trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Food provided by researchers
Who paid for it
- Funding
- Independent funding
- Government
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Government
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
Based on 2 listed funder(s).
Publication
- Published
- 2013-05-28 · Ren Fail · vol. 35 · issue 6 · pp. 830–834
- Publisher
- Taylor & Francis
- Cited
- 11 citations · more than 57% of similar papers · 0.3× the field average
- References
- 29 works
- Access
- Paywalled
- Research areas
- Dialysis and Renal Disease Management · Nutrition and Health in Aging · Nutritional Studies and Diet
- Keywords
- Medicine, Hemodialysis, Dialysis, Malnutrition, C-reactive protein, Internal medicine, Calorie, Gastroenterology, Inflammation
- MeSH
- humans, kidney failure, chronic, protein-energy malnutrition, inflammation, c-reactive protein, renal dialysis, prospective studies, pilot projects, nutritional status, meat, adult, middle aged, female, male, young adult
6 authors
From BR
- Isolda Prado de Negreiros Nogueira Maduro · correspondingUniversidade de Ribeirão Preto; Universidade de São Paulo; Universidade do Estado do Amazonas
- Carla Barbosa NoninoUniversidade do Estado do Amazonas
- Luiz Maçao SakamotoClinics Hospital of Ribeirão Preto
- Maurício Gomes MeirellesUniversidade de Ribeirão Preto
- José Abrão Cardeal da Costa
- Júlio Sérgio MarchiniUniversidade do Estado do Amazonas
Abstract
Rational
Among the alternatives to reverse chronic hemodialysis protein-energy malnutrition is the enhancement of intradialytic oral nutritional therapy. Although foods of animal origin are a source of nutrients and represent a feasible diet, there is uncertainty about their health consequences.
Objectives
We assessed the relationship of intradialytic high-protein red meat snack supplementation with patient inflammatory status and protein losses (nitrogen) during this supplementation. Fourteen patients submitted to low-flux chronic hemodialysis for one month were divided into two groups receiving 2 g (group 1) and 29 g (group 2) of oral intradialytic protein during the initial phase, respectively. In the subsequent phase, group 1 was supplemented with 27 g protein (a red meat snack) for a total of 29 g per dialysis. Group 2 continued to receive 29 g protein. Nutritional status, total nitrogen losses through the dialysate and acute inflammatory phase protein (CRP) were assessed before and after dialysis. Reuse of the dialyzer was also determined on each occasion.
Main findings
Red meat supplementation did not interfere with CRP, nitrogen loss through the dialysate (18 ± 7 to 19 ± 4 g in group 1, ns, and 20 ± 7 to 21 ± 4 g in group 2, ns) or with nutritional status. However, the data showed a positive correlation between pre- and post-hemodialysis CRP values (r = 0.84, p < 0.01) in both groups, suggesting an increase of the values after ultrafiltration. Reuse of the dialyzer was not correlated with CRP values.
Principle conclusions
The results suggest that snacks were not acutely correlated with increased inflammatory levels and indicated that a protein-rich red meat snack may be beneficial for chronic hemodialysis patients.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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