Effect of low level laser therapy in the reduction of oral complications in patients with cancer of the head and neck submitted to radiotherapy
Oton-Leite AF, Elias LS, Morais MO, Pinezi JC, Leles CR, Silva MA, Mendonça EF
Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry · 51 citations
How it was studied
- Design
- Randomized controlled trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- Government
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
Based on 1 listed funder(s).
Publication
- Published
- 2012-12-05 · Spec Care Dentist · vol. 33 · issue 6 · pp. 294–300
- Publisher
- Wiley
- Cited
- 77 citations · more than 89% of similar papers · 2.4× the field average
- References
- 50 works
- Access
- Paywalled
- Research areas
- Oral health in cancer treatment · Laser Applications in Dentistry and Medicine · Salivary Gland Disorders and Functions
- Keywords
- Medicine, Mucositis, Head and neck cancer, Radiation therapy, Low level laser therapy, Cancer, Laser therapy, Osteoradionecrosis, Surgery, Internal medicine, Laser
- MeSH
- humans, head and neck neoplasms, mouth diseases, radiotherapy, adult, aged, aged, 80 and over, middle aged, female, male, low-level light therapy
7 authors
From BR
- Angélica Ferreira Oton‐LeiteUniversidade Federal de Goiás
- Larissa Santana Arantes EliasUniversidade Federal de Goiás
- Marília Oliveira MoraisUniversidade Federal de Goiás
- Juliana Castro Dourado PineziHospital Araújo Jorge
- Cláudio Rodrigues Leles
- Maria Alves Garcia SilvaUniversidade Federal de Goiás
Abstract
The aim of this study was to assess the effect of low level laser therapy on reducing the occurrence and severity of oral complications in patients with head and neck cancer undergoing radiotherapy. Sixty head and neck cancer outpatients from a cancer hospital receiving radiotherapy were selected and randomly assigned into two groups. The laser group was irradiated with an InGaAlP laser and the control received sham laser. The assessment of complications (oral mucositis, pain) was carried out one week after starting radiotherapy, and at the fifteenth and thirtieth sessions of radiotherapy. All patients from both groups showed some degree of oral mucositis. Better outcomes were observed in the laser group when compared with the control in the follow-up sessions, indicating lower degrees of oral mucositis, pain and higher salivary flow (p < .05). These findings support the use of laser therapy as an adjuvant treatment for the control of oral complications.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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