Funded in part by Astellas Pharma, Astellas Foundation for Research on Metabolic Disorders
Processed meat consumption and lung function: modification by antioxidants and smoking
Okubo H, Shaheen SO, Ntani G, Jameson KA, Syddall HE, Sayer AA, Dennison EM, Cooper C, Robinson SM, Hertfordshire Cohort Study Group
The European respiratory journal · 41 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cohort study (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Food frequency questionnaire
Who paid for it
- Funding
- Industry funded
- Nonprofit
- Naito Foundation
- Government
- National Institute for Health and Care Research
- Company
- Astellas Pharma
- Company
- Astellas Foundation for Research on Metabolic Disorders
- Government
- Medical Research Council
- Government
- National Institute for Health Research (NIHR)
- Grants
- Medical Research Council (MC_UU_12011/4); National Institute for Health and Care Research (NF-SI-0508-10082); Medical Research Council (MC_UU_12011/2); Medical Research Council (MC_UU_12011/1); National Institute for Health and Care Research (NF-SI-0513-10085)
Based on 6 listed funder(s).
Publication
- Published
- 2013-10-31 · Eur Respir J · vol. 43 · issue 4 · pp. 972–982
- Publisher
- European Respiratory Society
- Cited
- 50 citations · more than 85% of similar papers · 1.8× the field average
- References
- 31 works
- Access
- Free to read
- Research areas
- Chronic Obstructive Pulmonary Disease (COPD) Research · Nutritional Studies and Diet · Asthma and respiratory diseases
- Keywords
- Lung function, Medicine, Vital capacity, Confounding, Consumption (sociology), Food frequency questionnaire, Food science, Food consumption, Cohort, Animal science, Environmental health, Lung, Internal medicine, Biology, Diffusing capacity
- MeSH
- lung, humans, fruit, vegetables, antioxidants, respiratory function tests, vital capacity, forced expiratory volume, treatment outcome, diet, cohort studies, feeding behavior, smoking, meat, aged, middle aged, female, male, united kingdom
10 authors
From GB, JP
- Hitomi OkuboMRC Lifecourse Epidemiology Unit; University of Southampton; The University of Tokyo
- Seif O. ShaheenQueen Mary University of London
- Georgia NtaniMRC Lifecourse Epidemiology Unit; University of Southampton
- Anthony JamesMRC Lifecourse Epidemiology Unit; University of Southampton
- Holly E. SyddallMRC Lifecourse Epidemiology Unit; University of Southampton
- Avan Aihie SayerMRC Lifecourse Epidemiology Unit; University of Southampton
Abstract
Unhealthy dietary patterns are associated with poor lung function. It is not known whether this is due to low consumption of antioxidant-rich fruit and vegetables, or is a consequence of higher intakes of harmful dietary constituents, such as processed meat. We examined the individual and combined associations of processed meat, fruit and vegetable consumption and dietary total antioxidant capacity (TAC) with lung function among 1551 males and 1391 females in the UK in the Hertfordshire Cohort Study. Diet was assessed using a food frequency questionnaire. After controlling for confounders, processed meat consumption was negatively associated with forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and FEV1/FVC ratio in males and females, while fruit and vegetable consumption and dietary TAC were positively associated with FEV1 and FVC, but not FEV1/FVC ratio. In males, the negative association between processed meat consumption and FEV1 was more marked in those who had low fruit and vegetable consumption (p=0.035 for interaction), and low dietary TAC (p=0.025 for interaction). The deficit in FEV1/FVC associated with processed meat consumption was larger in males who smoked (p=0.022 for interaction). Higher processed meat consumption is associated with poorer lung function, especially in males who have lower fruit and vegetable consumption or dietary TAC, and among current smokers.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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