Study2014

Guidance on water intake effectively improves urinary frequency in patients with nocturia

Tani M, Hirayama A, Torimoto K, Matsushita C, Yamada A, Fujimoto K

International journal of urology : official journal of the Japanese Urological Association · 23 citations

Review labels

Funding not disclosed

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Controlled clinical trial (classified by our AI screen)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Funding not disclosed

Publication

Published
2014-01-09 · Int J Urol · vol. 21 · issue 6 · pp. 595–600
Publisher
Wiley
Cited
34 citations · more than 84% of similar papers · 2.1× the field average
References
21 works
Access
Open access (repository copy) · CC-BY-NC-ND
Research areas
Urinary Bladder and Prostate Research · Thermoregulation and physiological responses · Circadian rhythm and melatonin
Keywords
Nocturia, Medicine, Evening, Urine, Water intake, Morning, Adverse effect, Nocturnal, Urinary system, Urology, Internal medicine
MeSH
humans, water deprivation, counseling, drinking, aged, male, nocturia

6 authors

From JP

  • Mitsuru Tani · correspondingNara Medical University Hospital; Nara Medical University
  • Akihide HirayamaNara Medical University Hospital; Nara Medical University
  • Kazumasa TorimotoNara Medical University Hospital; Nara Medical University
  • Chie MatsushitaNara Medical University Hospital; Nara Medical University
  • Atsushi YamadaNara Medical University Hospital; Nara Medical University
  • Kiyohide FujimotoNara Medical University Hospital; Nara Medical University

Abstract

Objectives

To evaluate how guidance on water-intake impacts the degree of nocturia.

Methods

A total of 67 male patients were enrolled in the present study. Patients were asked to adjust their water and food intakes so that their 24-h urine production/bodyweight would be equal or lower than 30 mL/kg. One month after the treatment, the therapeutic gain from and adverse effects of fluid restriction were examined by comparing the pretreatment and post-treatment value of various parameters.

Results

Overall, 65 eligible patients were evaluated. In 44 patients (67%), the frequency of nocturia was improved to one or more times. The change in frequency of nocturia showed a positive correlation with the change in nocturnal urine volume. The change in nocturnal urine volume showed a positive correlation with the changes in 24-h urine production/bodyweight, 24-h drinking volume and daytime drinking volume. The changes in 24-h urine production/bodyweight and daytime drinking volume were independent factors influencing therapeutic effect. None of the participants reported any adverse event.

Conclusions

In patients with a 24-h urine production/bodyweight equal or higher than 30 mL/kg, guidance on water intake might be considered effective and safe as a lifestyle therapy. Water restriction should be carried out not only in the evening, but also during daytime.

Abstract via Europe PMC. Copyright remains with the authors or publisher.

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