Effects of dietary nitrates on systemic and cerebrovascular hemodynamics
Bond V, Curry BH, Adams RG, Asadi MS, Millis RM, Haddad GE
Cardiology research and practice · 29 citations
How it was studied
- Design
- Controlled clinical trial (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Not stated
Who paid for it
- Funding
- Independent funding
- Government
- National Institutes of Health
- Government
- National Institute on Alcohol Abuse and Alcoholism
- Government
- National Center for Research Resources
- Government
- NCRR NIH HHS
- Government
- NIAAA NIH HHS
- Grants
- National Center for Research Resources (G12 RR003048); National Center for Research Resources (2G12-RR003048); National Institutes of Health (2G12 RR003048); National Institute on Alcohol Abuse and Alcoholism (R15 AA019816)
Based on 5 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2013-01-01 · Cardiol Res Pract · vol. 2013 · pp. 1–9
- Publisher
- Hindawi Publishing Corporation
- Cited
- 48 citations · more than 87% of similar papers · 1.9× the field average
- References
- 42 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Blood Pressure and Hypertension Studies · Cardiovascular Health and Disease Prevention · Heart Rate Variability and Autonomic Control
- Keywords
- Medicine, Blood pressure, Hemodynamics, Cardiology, Vascular resistance, Cerebral blood flow, Internal medicine, Blood flow, Heart rate
6 authors
From US
- Vernon BondHoward University
- Bryan H CurryHoward University Hospital
- Richard G. AdamsHoward University Hospital
- Mohammad Sadegh AsadiHoward University Hospital
- Richard Mark Millis · correspondingHoward University
- Georges E. HaddadHoward University
Abstract
Cerebral blood flow dysregulation is often associated with hypertension. We hypothesized that a beetroot juice (BRJ) treatment could decrease blood pressure and cerebrovascular resistance (CVR). We subjected 12 healthy females to control and BRJ treatments. Cerebrovascular resistance index (CVRI), systolic blood pressure (SBP), total vascular resistance (TVR), and the heart rate-systolic pressure product (RPP) measured at rest and at two exercise workloads were lower after the BRJ treatment. CVRI, SBP, and RPP were lower without a lower TVR at the highest exercise level. These findings suggest improved systemic and cerebral hemodynamics that could translate into a dietary treatment for hypertension.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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