Cohort study2014

Intakes of potassium, magnesium, and calcium and risk of stroke

Sluijs I, Czernichow S, Beulens JW, Boer JM, van der Schouw YT, Verschuren WM, Grobbee DE

Stroke · 27 citations

Review labels

Funding not disclosed

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Cohort study (indexed by PubMed)
Studied in
People
Main outcome
Clinical events such as disease or death

Who paid for it

Funding
Funding not disclosed

Publication

Published
2014-02-12 · Stroke · vol. 45 · issue 4 · pp. 1148–1150
Publisher
Lippincott Williams & Wilkins
Cited
38 citations · more than 94% of similar papers · 4.3× the field average
Impact
Top 10% most cited in its field
References
15 works
Access
Free to read
Research areas
Magnesium in Health and Disease · Parathyroid Disorders and Treatments · Sodium Intake and Health
Keywords
Medicine, Magnesium, Stroke (engine), Hazard ratio, Potassium, Confounding, Calcium, Confidence interval, Prospective cohort study, Internal medicine, Cohort study
MeSH
humans, calcium, dietary, magnesium, potassium, dietary, nutrition assessment, incidence, proportional hazards models, risk factors, follow-up studies, prospective studies, risk reduction behavior, adult, aged, middle aged, female, male, stroke, young adult

7 authors

From FR, NL

  • Ivonne SluijsInserm; University Medical Center Utrecht; Centre de recherche en Epidémiologie et Santé des Populations; National Institute for Public Health and the Environment
  • Sébastien CzernichowInserm; University Medical Center Utrecht; Centre de recherche en Epidémiologie et Santé des Populations; National Institute for Public Health and the Environment
  • Joline W. J. BeulensInserm; University Medical Center Utrecht; Centre de recherche en Epidémiologie et Santé des Populations; National Institute for Public Health and the Environment
  • Jolanda M.A. BoerInserm; University Medical Center Utrecht; Centre de recherche en Epidémiologie et Santé des Populations; National Institute for Public Health and the Environment
  • Yvonne T. van der SchouwInserm; University Medical Center Utrecht; Centre de recherche en Epidémiologie et Santé des Populations; National Institute for Public Health and the Environment
  • W. M. Monique VerschurenInserm; University Medical Center Utrecht; Centre de recherche en Epidémiologie et Santé des Populations; National Institute for Public Health and the Environment

Abstract

Background and purpose

We aimed to investigate the associations of dietary and total potassium, magnesium, and calcium intakes with stroke occurrence.

Methods

A prospective cohort study was conducted among 36 094 participants aged 21 to 70 years. Dietary intake was assessed with a food frequency questionnaire.

Results

During 12 years of follow-up, 631 strokes occurred. After adjustment for confounders, magnesium intake was associated with reduced stroke risk (hazard ratio [95% confidence interval] per 100 mg/d, 0.80 [0.67-0.97] dietary magnesium; 0.78 [0.65-0.93] total magnesium). Potassium and calcium intakes were not associated with stroke.

Conclusions

This study supports an association between high magnesium intake and a reduced stroke risk.

Abstract via Europe PMC. Copyright remains with the authors or publisher.

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