Funded in part by Egg Nutrition Center
Egg consumption and cardiovascular disease among diabetic individuals: a systematic review of the literature
Tran NL, Barraj LM, Heilman JM, Scrafford CG
Diabetes, metabolic syndrome and obesity : targets and therapy · 27 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Systematic review (classified by our AI screen)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Not stated
Who paid for it
- Funding
- Industry funded
- Industry group
- Egg Nutrition Center
Based on 1 listed funder(s).
Publication
- Published
- 2014-03-01 · Diabetes Metab Syndr Obes · vol. 7 · p. 121
- Publisher
- Dove Medical Press
- Cited
- 44 citations · more than 73% of similar papers · 1.4× the field average
- References
- 81 works
- Access
- Open access (journal) · CC-BY-NC
- Research areas
- Nutritional Studies and Diet · Consumer Attitudes and Food Labeling · Food composition and properties
- Keywords
- Confounding, Medicine, Disease, Diabetes mellitus, Type 2 Diabetes Mellitus, Epidemiology, Type 2 diabetes, Meta-analysis, Metabolic syndrome, Stroke (engine), Internal medicine, Prospective cohort study, Environmental health, Endocrinology
4 authors
From US
- Nga L. TranExponent (United States)
- Leila M. BarrajExponent (United States)
- Jacqueline M. HeilmanExponent (United States)
- Carolyn ScraffordExponent (United States)
Abstract
Background
This study reviewed epidemiological and experimental evidence on the relationship between egg consumption and cardiovascular disease (CVD) risks among type II diabetes mellitus (T2DM) individuals, and T2DM risk in nondiabetic subjects.
Results
Four of the six studies that examined CVD and mortality and egg consumption among diabetics found a statistically significant association. Of the eight studies evaluating incident T2DM and egg consumption, four prospective studies found a statistically significant association. Lack of adjustment for dietary confounders was a common study limitation. A small number of experimental studies examined the relationship between egg intake and CVD risk biomarkers among diabetics or individuals with T2DM risk factors. Studies among healthy subjects found suggestive evidence that dietary interventions that include eggs may reduce the risk of T2DM and metabolic syndrome.
Conclusion
Differences in study design, T2DM status, exposure measurement, subject age, control for confounders and follow-up time present significant challenges for conducting a meta-analysis. Conflicting results, coupled with small sample sizes, prevent broad interpretation. Given the study limitations, these findings need to be further investigated.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY-NC).
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