Association between total, processed, red and white meat consumption and all-cause, CVD and IHD mortality: a meta-analysis of cohort studies
Abete I, Romaguera D, Vieira AR, Lopez de Munain A, Norat T
The British journal of nutrition · 302 citations
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Not stated
Who paid for it
- Funding
- Independent funding
- Government
- Instituto de Salud Carlos III
- Grants
- Instituto de Salud Carlos III (CD11/00196)
Based on 1 listed funder(s).
Publication
- Published
- 2014-06-16 · Br J Nutr · vol. 112 · issue 5 · pp. 762–775
- Publisher
- Cambridge University Press
- Cited
- 453 citations · more than 97% of similar papers · 4.6× the field average
- Impact
- Top 10% most cited in its field
- References
- 44 works
- Access
- Free to read
- Research areas
- Nutritional Studies and Diet · Consumer Attitudes and Food Labeling · Obesity, Physical Activity, Diet
- Keywords
- Medicine, Meta-analysis, Cause of death, Cohort study, White (mutation), Environmental health, Cohort, White meat, Disease, Internal medicine, Demography, Biology, Food science, Genetics
- MeSH
- animals, humans, cardiovascular diseases, myocardial ischemia, diet, cause of death, cohort studies, prospective studies, food handling, meat, meat products, adolescent, adult, aged, aged, 80 and over, middle aged, united states, asia, australia, europe, female, male
5 authors
From ES, GB
- Itziar Abete · correspondingBiogipuzkoa Health Research Institute; St Mary's Hospital; Imperial College London
- Dora RomagueraSt Mary's Hospital; Ministry of Economy, Industry and Competitiveness; Ministerio de Economía y Competitividad; Imperial College London
- Ana VieiraSt Mary's Hospital; Imperial College London
- Adolfo López de MunaínUniversity of the Basque Country; Biomedical Research Networking Center on Neurodegenerative Diseases; Biogipuzkoa Health Research Institute; Ministry of Economy, Industry and Competitiveness; Ministerio de Economía y Competitividad
- Teresa NoratSt Mary's Hospital; Imperial College London
Abstract
An association between processed and red meat consumption and total mortality has been reported by epidemiological studies; however, there are many controversial reports regarding the association between meat consumption and CVD and IHD mortality. The present meta-analysis was carried out to summarise the evidence from prospective cohort studies on the association between consumption of meat (total, red, white and processed) and all-cause, CVD and IHD mortality. Cohort studies were identified by searching the PubMed and ISI Web of Knowledge databases. Risk estimates for the highest v. the lowest consumption category and dose-response meta-analysis were calculated using a random-effects model. Heterogeneity among the studies was also evaluated. A total of thirteen cohort studies were identified (1 674 272 individuals). Subjects in the highest category of processed meat consumption had 22 and 18 % higher risk of mortality from any cause and CVD, respectively. Red meat consumption was found to be associated with a 16 % higher risk of CVD mortality, while no association was found for total and white meat consumption. In the dose-response meta-analysis, an increase of 50 g/d in processed meat intake was found to be positively associated with all-cause and CVD mortality, while an increase of 100 g/d in red meat intake was found to be positively associated with CVD mortality. No significant associations were observed between consumption of any type of meat and IHD mortality. The results of the present meta-analysis indicate that processed meat consumption could increase the risk of mortality from any cause and CVD, while red meat consumption is positively but weakly associated with CVD mortality. These results should be interpreted with caution due to the high heterogeneity observed in most of the analyses as well as the possibility of residual confounding.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
Community trust
Loading…
How much do you trust this study's findings?
Comments
Sign in to rate, comment on or flag this study.Sign inSomething wrong here?
Flag this study if its information, labels or funding look wrong. An editor reviews every flag.
Sign in to rate, comment on or flag this study.Sign inEducational information about published research. Not medical advice, and not a recommendation to start or stop anything.