Funded in part by Alpro Foundation
Impact of processing on the bioavailability and vascular effects of blueberry (poly)phenols
Rodriguez-Mateos A, Del Pino-García R, George TW, Vidal-Diez A, Heiss C, Spencer JP
Molecular nutrition & food research · 87 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Randomized controlled trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Food provided by researchers
Who paid for it
- Funding
- Industry funded
- Company
- Alpro Foundation
Based on 1 listed funder(s).
Publication
- Published
- 2014-07-15 · Mol Nutr Food Res · vol. 58 · issue 10 · pp. 1952–1961
- Publisher
- Wiley
- Cited
- 123 citations · more than 96% of similar papers · 4.6× the field average
- Impact
- Top 10% most cited in its field
- References
- 34 works
- Access
- Paywalled
- Research areas
- Phytochemicals and Antioxidant Activities · Food composition and properties · Alcohol Consumption and Health Effects
- Keywords
- Bioavailability, Phenols, Food science, Chemistry, Metabolite, Breakfast cereal, Chlorogenic acid, Crossover study, Biochemistry, Biology, Pharmacology, Medicine
- MeSH
- brachial artery, endothelium, vascular, humans, fruit, flavonoids, freeze drying, cross-over studies, vasodilation, intestinal absorption, postprandial period, kinetics, food handling, beverages, adolescent, adult, male, young adult, fast foods, polyphenols, blueberry plants
6 authors
From DE, GB, ES
- Ana Rodriguez‐Mateos · correspondingHeinrich Heine University Düsseldorf; University of Reading
- Raquel Del Pino‐GarcíaUniversidad de Burgos; University of Reading
- Trevor W. GeorgeNorthumbria University
- Alberto Vidal‐DiezSt George's, University of London
- Christian HeißHeinrich Heine University Düsseldorf
- Jeremy P. E. SpencerUniversity of Reading
Abstract
Scope
Blueberries are a rich source of flavonoids and phenolic acids. Currently, little information is available regarding the impact of processing on the bioavailability and the bioactivity of blueberry (poly)phenols.
Methods and results
In a randomized, controlled crossover trial, ten healthy volunteers consumed (a) blueberry-containing baked products, (b) an unprocessed blueberry drink containing the same amount of freeze-dried blueberry powder as used in the baked products, and (c) matched control baked products. Endothelial function was measured as flow-mediated dilation (FMD) and plasma samples taken at baseline and at 1, 2, 4, and 6 h postconsumption. Although processing did not significantly change the total (poly)phenolic amount, the processed products contained significantly less anthocyanins (-42%), more chlorogenic acid (23%), no flavanol nonamers or decamers, and significantly more flavanol dimers and trimers (36% and 28%, respectively). FMD increased after 1, 2, and 6 h consumption of the baked products to a similar degree as the unprocessed blueberries, despite significant differences in the levels of individual plasma metabolites. No changes were observed after the consumption of the control product.
Conclusion
Careful processing can preserve important biological activities of blueberries despite changing the blueberry (poly)phenol composition and plasma metabolite profile.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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