Chromium in drinking water: association with biomarkers of exposure and effect
Sazakli E, Villanueva CM, Kogevinas M, Maltezis K, Mouzaki A, Leotsinidis M
International journal of environmental research and public health · 24 citations
How it was studied
- Design
- Cross-sectional study (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
Based on full-text disclosure statement.
Publication
- Published
- 2014-09-29 · Int J Environ Res Public Health · vol. 11 · issue 10 · pp. 10125–10145
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 43 citations · more than 84% of similar papers · 2.1× the field average
- References
- 50 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Chromium effects and bioremediation · Adsorption and biosorption for pollutant removal · Mercury impact and mitigation studies
- Keywords
- Environmental health, Association (psychology), Chromium, Exposure assessment, Medicine, Environmental chemistry, Chemistry, Psychology
- MeSH
- hair, humans, sodium, chromium, triglycerides, water pollutants, chemical, diet, cross-sectional studies, motor activity, water supply, adult, aged, middle aged, greece, female, male, drinking water, biomarkers
6 authors
From GR, ES
- Eleni SazakliUniversity of Patras
- Cristina M. VillanuevaUniversitat Pompeu Fabra; Center for Research in Environmental Epidemiology; Hospital Del Mar; Municipal Institute for Medical Research; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública; Hospital del Mar Research Institute
- Manolis KogevinasUniversitat Pompeu Fabra; Center for Research in Environmental Epidemiology; National School of Public Health; Hospital Del Mar; Municipal Institute for Medical Research; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública; Hospital del Mar Research Institute
- Kyriakos Maltezis
- Αthanasia MouzakiUniversity of Patras
- Michalis Leotsinidis · correspondingUniversity of Patras
Abstract
An epidemiological cross-sectional study was conducted in Greece to investigate health outcomes associated with long-term exposure to chromium via drinking water. The study population consisted of 304 participants. Socio-demographics, lifestyle, drinking water intake, dietary habits, occupational and medical history data were recorded through a personal interview. Physical examination and a motor test were carried out on the individuals. Total chromium concentrations were measured in blood and hair of the study subjects. Hematological, biochemical and inflammatory parameters were determined in blood. Chromium in drinking water ranged from <0.5 to 90 μg·L-1 in all samples but one (220 μg·L-1), with a median concentration of 21.2 μg·L-1. Chromium levels in blood (median 0.32 μg·L-1, range <0.18-0.92 μg·L-1) and hair (median 0.22 μg·g-1, range 0.03-1.26 μg·g-1) were found within "normal range" according to the literature. Personal lifetime chromium exposure dose via drinking water, calculated from the results of the water analyses and the questionnaire data, showed associations with blood and hair chromium levels and certain hematological and biochemical parameters. Groups of subjects whose hematological or biochemical parameters were outside the normal range were not correlated with chromium exposure dose, except for groups of subjects with high triglycerides or low sodium. Motor impairment score was not associated with exposure to chromium.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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