Red meat intake and risk of non-Hodgkin lymphoma: a meta-analysis
Fallahzadeh H, Cheraghi M, Amoori N, Alaf M
Asian Pacific journal of cancer prevention : APJCP · 14 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Not stated
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2015-01-06 · Asian Pac J Cancer Prev · vol. 15 · issue 23 · pp. 10421–10425
- Publisher
- West Asia Organization for Cancer Prevention
- Cited
- 16 citations · more than 47% of similar papers · 0.4× the field average
- References
- 26 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Lymphoma Diagnosis and Treatment · Antioxidant Activity and Oxidative Stress · Lymphadenopathy Diagnosis and Analysis
- Keywords
- Hodgkin lymphoma, Lymphoma, Medicine, Meta-analysis, Environmental health, Oncology, Internal medicine
- MeSH
- animals, cattle, swine, humans, lymphoma, non-hodgkin, lymphoma, follicular, odds ratio, risk factors, feeding behavior, food handling, meat, meat products, leukemia, lymphocytic, chronic, b-cell, lymphoma, large b-cell, diffuse
4 authors
From IR
- Hosein FallahzadehShahid Sadoughi University of Medical Sciences and Health Services
- Maria Cheraghi
- Neda Amoori
- Mehrangiz Alaf
Abstract
Background
While the incidence of non-Hodgkins lymphoma (NHL) has been rising worldwide, the reasons remain undefined. Recent research has focused on effect of red andf processed meat intake as a risk factor, but with inconclusive results. We therefore conducted a meta-analysis of data published to date, to ascertain the overall association between intake and NHL.
Materials and methods
A published literature search was performed through Pubmed, Cochrane Library, Medline, and Science Citation Index Expanded databases for articles published in English. Pooled odds ratios (ORs) and 95% confidence intervals (95%CIs) were calculated using random or fixed effects models. Heterogeneity was assessed using Chi-square and I2 statistics. Dissemination bias was evaluated by funnel plot analysis.We performed a formal meta-analysis using summary measures from these studies.
Results
In total, 11 published studies were included in the final analysis. The combined analysis revealed that there was significant association between the red meat and NHL risk (OR=1.10, 95%CI: 1.02 to 1.19, p=0.01). Additionally, there was showed significance association between processed red meat and NHL risk (OR=1.17, 95%CI: 1.06 to 1.29, p=0.001). In subgroup analysis, a statistical significant association was noted between diffuse large B-cell lymphoma (DLBCL) (OR=1.20, 95%CI: 1.04 to 2.37, P=0.01) and red meat intake.
Conclusions
In this meta-Analysis, there was evidence for association between consumption of red meat, or processed meat and risk of NHL, particularly with the DLBCL subtype in the red meat case.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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