Effects of caffeine and maltodextrin mouth rinsing on P300, brain imaging, and cognitive performance
De Pauw K, Roelands B, Knaepen K, Polfliet M, Stiens J, Meeusen R
Journal of applied physiology (Bethesda, Md. : 1985) · 50 citations
How it was studied
- Design
- Randomized controlled trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- Government
- European Commission
- Government
- Fund for Scientific Research Flanders
- Government
- European Commission (EC)
- Grants
- European Commission (287894)
Based on 3 listed funder(s).
Publication
- Published
- 2015-01-23 · J Appl Physiol (1985) · vol. 118 · issue 6 · pp. 776–782
- Publisher
- American Physiological Society
- Cited
- 82 citations · more than 93% of similar papers · 3.6× the field average
- Impact
- Top 10% most cited in its field
- References
- 49 works
- Access
- Paywalled
- Research areas
- Muscle metabolism and nutrition · Eating Disorders and Behaviors · Obesity, Physical Activity, Diet
- Keywords
- Stroop effect, Orbitofrontal cortex, Placebo, Brain activity and meditation, Maltodextrin, Crossover study, Audiology, Psychology, Effects of sleep deprivation on cognitive performance, Prefrontal cortex, Cognition, Medicine, Electroencephalography, Neuroscience, Chemistry, Pathology
- MeSH
- mouth, prefrontal cortex, humans, caffeine, polysaccharides, diagnostic imaging, electroencephalography, exercise, brain mapping, cross-over studies, double-blind method, cognition, reaction time, adult, male, e1a-associated p300 protein
6 authors
From BE, AU
- Kevin De PauwVrije Universiteit Brussel
- Bart RoelandsVrije Universiteit Brussel; Fund for Scientific Research
- Kristel KnaepenVrije Universiteit Brussel
- Mathias PolflietVrije Universiteit Brussel; iMinds
- Johan H. StiensVrije Universiteit Brussel
- ROMAIN R. MEEUSEN · correspondingVrije Universiteit Brussel; James Cook University
Abstract
Caffeine (CAF) and maltodextrin (MALT) mouth rinses (MR) improve exercise performance. The current experiment aims to determine the effect of CAF and MALT MR on cognitive performance and brain activity. Ten healthy male subjects (age 27 ± 3 yr) completed three experimental trials. Each trial included four Stroop tasks: two familiarization tasks, and one task before and one task after an MR period. The reaction time (in milliseconds) and accuracy (percent) of simple, congruent, and incongruent stimuli were assessed. Electroencephalography was applied throughout the experiment to record brain activity. The amplitudes and latencies of the P300 were determined during the Stroop tasks before and after the MR period. Subjects received MR with CAF (0.3 g/25 ml), MALT (1.6 g/25 ml), or placebo (PLAC) in a randomized, double-blind, crossover design. During MR, the brain imaging technique standardized low-resolution brain electromagnetic tomography was applied. Magnitude-based inferences showed that CAF MR is likely trivial (63.5%) and likely beneficial (36.4%) compared with PLAC MR, and compared with MALT MR likely beneficial to reaction time on incongruent stimuli (61.6%). Additionally, both the orbitofrontal and dorsolateral prefrontal cortex were activated only during CAF MR, potentially explaining the likely beneficial effect on reaction times. MALT MR increased brain activity only within the orbitofrontal cortex. However, this brain activation did not alter the reaction time. Furthermore, no significant differences in the accuracy of stimuli responses were observed between conditions. In conclusion, only CAF MR exerted a likely beneficial effect on reaction time due to the subsequent activation of both the orbitofrontal and dorsolateral prefrontal cortexes.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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