Intake of cruciferous vegetables is associated with reduced risk of ovarian cancer: a meta-analysis
Hu J, Hu Y, Hu Y, Zheng S
Asia Pacific journal of clinical nutrition · 33 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Not stated
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2015-01-01 · Asia Pac J Clin Nutr · vol. 24 · issue 1 · pp. 101–9
- Publisher
- National Institutes of Health
- Cited
- 51 citations · more than 93% of similar papers · 3.4× the field average
- Impact
- Top 10% most cited in its field
- References
- 38 works
- Access
- Paywalled
- Research areas
- Genomics, phytochemicals, and oxidative stress · Garlic and Onion Studies · Potato Plant Research
- Keywords
- Cruciferous vegetables, Meta-analysis, Medicine, Ovarian cancer, Publication bias, Relative risk, MEDLINE, Confidence interval, Cohort study, Internal medicine, Oncology, Web of science, Cancer, Gynecology, Biology
- MeSH
- humans, brassicaceae, ovarian neoplasms, diet, risk, case-control studies, cohort studies, adolescent, adult, aged, aged, 80 and over, middle aged, female
4 authors
- Jiyi Hu
- Yiwang Hu
- Yeting Hu
- Shu Sen Zheng
Abstract
Background
Epidemiological studies on the association between cruciferous vegetable (CV) consumption and the risk of ovarian cancer have demonstrated inconsistent results. We conducted a meta-analysis on CV consumption and ovarian cancer risk.
Methods
The relevant studies were identified by searching the Medline (Pubmed), Embase and Web of Science databases. The references of related articles and reviews up to October 2013 were also screened. The pooled relative risks (RRs) with 95% confidence intervals (CIs) for the highest versus the lowest CV consumption levels were calculated using a random-effects model. The heterogeneity and publication bias were also evaluated.
Results
Eight studies (4 case-control studies and 4 cohort studies) were identified and included in this meta-analysis. When all studies were pooled together, there was a significantly inverse association between CV consumption and the risk of ovarian cancer (RR: 0.89; 95% CI: 0.81-0.99). No significant heterogeneity or publication bias was found.
Conclusions
The findings from this study suggest that the consumption of CVs may reduce the risk of ovarian cancer. Further investigations are needed to confirm the clinical effect of CVs on ovarian cancer.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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