Biocompounds from rapeseed oil industry co-stream as active ingredients for skin care applications
Rivera D, Rommi K, Fernandes MM, Lantto R, Tzanov T
International journal of cosmetic science · 7 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- In vitro/mechanistic study (classified by our AI screen)
- Studied in
- Cells or lab samples
- Main outcome
- Mechanisms only
Who paid for it
- Funding
- Independent funding
- Government
- Seventh Framework Programme
- Grants
- Seventh Framework Programme (289170)
Based on 1 listed funder(s).
Publication
- Published
- 2015-03-31 · Int J Cosmet Sci · vol. 37 · issue 5 · pp. 496–505
- Publisher
- Wiley
- Cited
- 20 citations · more than 66% of similar papers · 0.6× the field average
- References
- 50 works
- Access
- Free to read
- Research areas
- Protein Hydrolysis and Bioactive Peptides · Enzyme Production and Characterization · Proteins in Food Systems
- Keywords
- Chemistry, Rapeseed, Antioxidant, Hydrolysate, Food science, Context (archaeology), Hydrolysis, Biochemistry
- MeSH
- humans, fatty acids, monounsaturated, plant oils, cosmetics, skin care, electrophoresis, polyacrylamide gel, hydrolysis, rapeseed oil
5 authors
From ES, FI
- Diana Rose T. RiveraUniversitat Politècnica de Catalunya
- Katariina RommiVTT Technical Research Centre of Finland
- Margarida M. FernandesUniversitat Politècnica de Catalunya
- Raija LanttoVTT Technical Research Centre of Finland
- Tzanko Tzanov · correspondingUniversitat Politècnica de Catalunya
Abstract
Objective
Despite the great number of substances produced by the skincare industry, very few of them seem to truly have an effect on the skin. Therefore, given the social implications surrounding physical appearance, the search for new bioactive compounds to prevent or attenuate skin ageing and enhance self-image is a priority of current research. In this context, being rich in valuable compounds, such as proteins, phenolics, lipids and vitamins, this study is focused on the potential activity of rapeseed press cake hydrolysates to be used as raw materials for skincare applications.
Methods
In this study, the protein-rich press residue from the rapeseed oil industry was converted enzymatically into short-chain biologically active peptides using four protease products with varying substrate specificity - Alcalase 2.4L FG, Protex 6L, Protamex and Corolase 7089. The antioxidant, anti-wrinkle and anti-inflammatory activities of the obtained hydrolysates were evaluated in vitro while their biocompatibility with human skin fibroblasts was tested.
Results
All hydrolysates were biocompatible with skin fibroblasts after 24 h of exposure, while the non-hydrolysed extract induced cell toxicity. Alcalase 2,4L FG and Protex 6L-obtained hydrolysates were the most promising extracts showing improved bioactivities suitable for skin anti-ageing formulations, namely antioxidant activity, inhibiting approximately 80% cellular reactive oxidative species, anti-inflammatory and anti-wrinkle properties, inhibiting around 36% of myeloperoxidase activity and over 83% of elastase activity.
Conclusion
The enzymatic technology applied to the rapeseed oil industry costream results in the release of bioactive compounds suitable for skincare applications.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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