Measurement of Choroidal Thickness Following Caffeine Intake in Healthy Subjects
Altinkaynak H, Ceylan E, Kartal B, Keleş S, Ekinci M, Olcaysu OO
Current eye research · 47 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cohort study (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2015-04-10 · Curr Eye Res · vol. 41 · issue 5 · pp. 1–8
- Publisher
- Taylor & Francis
- Cited
- 49 citations · more than 87% of similar papers · 2.2× the field average
- References
- 55 works
- Access
- Paywalled
- Research areas
- Coffee research and impacts · Drug-Induced Ocular Toxicity · Retinal Diseases and Treatments
- Keywords
- Caffeine, Medicine, Capsule, Ophthalmology, Anesthesia, Nuclear medicine, Internal medicine
- MeSH
- choroid, humans, caffeine, central nervous system stimulants, tomography, optical coherence, administration, oral, follow-up studies, prospective studies, dose-response relationship, drug, adult, middle aged, female, male, young adult, healthy volunteers
6 authors
From TR
- Hasan Altınkaynak · correspondingAnkara Atatürk Eğitim ve Araştırma Hastanesi
- Erdinç CeylanErzurum Regional Training and Research Hospital
- Baki KartalErzurum Regional Training and Research Hospital
- Sadullah KeleşAtatürk University
- Metin EkinciKafkas University
- Osman Okan OlcaysüErzurum Regional Training and Research Hospital
Abstract
Purpose
The aim of this study is to investigate the effect of 200 mg caffeine on subfoveal choroidal thickness (CT) in the macular area as measured by enhanced depth imaging optical coherence tomography (EDI-OCT) in healthy subjects.
Materials and methods
Fifty healthy individuals (study group) and 50 healthy individuals (control group) were enrolled in study. In the study group, participants received a 200 mg caffeine capsule and the control group consisted of subjects who received plasebo capsule. The subfoveal CT was measured by EDI-OCT before the caffeine intake and at 30 min, 1 h, 2 h, 3 h, 4 h and 6 h following caffeine intake.
Results
SFCT after caffeine intake was significantly decreased at 30 min, 1 h, 2 h, 3 h and 4 h compared to the baseline measurement, while the difference between baseline and 6 h was not statistically significant in the study group. There were no significant differences between the baseline and the other measurement times in the control group (p > 0.05).
Conclusion
The thinning of CT begins about 30 min after the oral ingestion of 200 mg of caffeine and lasts for about four hours.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
Community trust
Loading…
How much do you trust this study's findings?
Comments
Sign in to rate, comment on or flag this study.Sign inSomething wrong here?
Flag this study if its information, labels or funding look wrong. An editor reviews every flag.
Sign in to rate, comment on or flag this study.Sign inEducational information about published research. Not medical advice, and not a recommendation to start or stop anything.