Low-level laser therapy in the treatment of recurrent aphthous ulcers: a systematic review
Vale FA, Moreira MS, de Almeida FC, Ramalho KM
TheScientificWorldJournal · 19 citations
How it was studied
- Design
- Systematic review (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
Based on full-text disclosure statement.
Publication
- Published
- 2015-01-01 · ScientificWorldJournal · vol. 2015 · issue 1 · p. 150412
- Publisher
- Hindawi Publishing Corporation
- Cited
- 52 citations · more than 69% of similar papers · 1.0× the field average
- References
- 73 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Laser Applications in Dentistry and Medicine · Oral Health Pathology and Treatment · Nail Diseases and Treatments
- Keywords
- Low level laser therapy, Medicine, Randomized controlled trial, Laser therapy, Treatment protocol, Recurrent aphthous stomatitis, Lesion, Systematic review, Stomatitis, Surgery, MEDLINE, Dermatology, Laser
- MeSH
- mouth, animals, humans, stomatitis, aphthous, recurrence, randomized controlled trials as topic, laser therapy, low-level light therapy
4 authors
From BR
- Fernando Alves ValeUniversidade Ibirapuera
- Maria Stella MoreiraUniversidade Ibirapuera
- Fernanda Campos Souza de AlmeidaUniversidade de São Paulo
- Karen Müller Ramalho · correspondingUniversidade Ibirapuera
Abstract
Recurrent aphthous ulcers (RAUs) are the most common lesion found in the oral cavity. There is no definitive cure for RAUs and current treatments are aimed at minimizing symptoms. Since low-level laser therapy (LLLT) modulates inflammatory responses, and promotes pain reduction and cellular biostimulation, LLLT can be suggested as an alternative treatment for RAUs. The literature concerning the potential of LLLT in the treatment of RAUs was evaluated. A systematic literature review identified 22 publications, of which only 2 studies were adopted. The eligibility criteria consisted of randomized controlled trials (RCTs). Both RCTs achieved significant results concerning LLLT and pain-level reductions and reduced healing times. Despite the variance in irradiation conditions applied in both studies, very similar wavelengths were adopted. There is accordingly strong evidence that wavelength plays an important role in RAU treatment. Taking into account the different parameters applied by selected RCTs, it is not possible to suggest that a specific protocol should be used. However, in light of the significant results found in both studies, LLLT can be suggested as an alternative for RAU treatment. Additional RCTs should be performed in order to reach a clinical protocol and better understand the application of LLLT in RAU treatment.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
Community trust
Loading…
How much do you trust this study's findings?
Comments
Sign in to rate, comment on or flag this study.Sign inSomething wrong here?
Flag this study if its information, labels or funding look wrong. An editor reviews every flag.
Sign in to rate, comment on or flag this study.Sign inEducational information about published research. Not medical advice, and not a recommendation to start or stop anything.