Cruciferous vegetable consumption and the risk of pancreatic cancer: a meta-analysis
Li LY, Luo Y, Lu MD, Xu XW, Lin HD, Zheng ZQ
World journal of surgical oncology · 38 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Not stated
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2015-02-11 · World J Surg Oncol · vol. 13 · issue 1 · p. 44
- Publisher
- BioMed Central
- Cited
- 47 citations · more than 40% of similar papers · 0.3× the field average
- References
- 43 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Genomics, phytochemicals, and oxidative stress · Vitamin C and Antioxidants Research · Alcohol Consumption and Health Effects
- Keywords
- Medicine, Surgical oncology, Meta-analysis, Pancreatic cancer, Oncology, Consumption (sociology), Cruciferous vegetables, Internal medicine, Environmental health, Cancer
- MeSH
- humans, vegetables, pancreatic neoplasms, prognosis, diet, risk factors, case-control studies
6 authors
From CN
- Liyi LiWenzhou Medical University; Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
- Yue LuoWenzhou Medical University; Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
- Mingdong LuWenzhou Medical University; Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
- Xiaowu XuWenzhou Medical University; Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
- Hai-duo LinWenzhou Medical University; Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
- Zhiqiang Zheng · correspondingWenzhou Medical University; Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
Abstract
Background
Previous studies regarding the association between cruciferous vegetable intake and pancreatic cancer risk have reported inconsistent results. We conducted a meta-analysis to demonstrate the potential association between them.
Methods
A systematic literature search of papers was conducted in March 2014 using PubMed, EMBASE, and Web of Science, and the references of the retrieved articles were screened. The summary odds ratios (ORs) with 95% confidence interval (CI) for the highest versus the lowest intake of cruciferous vegetables were calculated.
Results
Four cohort and five case-control studies were eligible for inclusion. We found a significantly decreased risk of pancreatic cancer associated with the high intake of cruciferous vegetables (OR 0.78, 95% CI 0.64-0.91). Moderate heterogeneity was detected across studies (P = 0.065). There was no evidence of significant publication bias based on Begg's funnel plot (P = 0.917) or Egger's test (P = 0.669).
Conclusions
Cruciferous vegetable intake might be inversely associated with pancreatic cancer risk. Because of the limited number of studies included in this meta-analysis, further well-designed prospective studies are warranted to confirm the inverse association between cruciferous vegetable intake and risk of pancreatic cancer.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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