Effect of short-term exercise-heat acclimation on ventilatory and cerebral blood flow responses to passive heating at rest in humans
Fujii N, Tsuji B, Honda Y, Kondo N, Nishiyasu T
Journal of applied physiology (Bethesda, Md. : 1985) · 20 citations
How it was studied
- Design
- Controlled clinical trial (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- University or hospital
- University of Tsukuba
- Government
- Japan Society for the Promotion of Science
- Government
- Ministry of Education, Science, and Culture of Japan
- Government
- Japan Society of the Promotion of Science
- Unclassified
- The Center of Excellence (COE)
- Grants
- Japan Society for the Promotion of Science (25242061)
Based on 5 listed funder(s).
Publication
- Published
- 2015-07-09 · J Appl Physiol (1985) · vol. 119 · issue 5 · pp. 435–444
- Publisher
- American Physiological Society
- Cited
- 26 citations · more than 77% of similar papers · 1.1× the field average
- References
- 57 works
- Access
- Paywalled
- Research areas
- Thermoregulation and physiological responses · Climate Change and Health Impacts · Thermal Regulation in Medicine
- Keywords
- Hyperventilation, Ventilation (architecture), Thermoregulation, Respiratory minute volume, Medicine, Hyperthermia, Chemistry, Cerebral blood flow, Anesthesia, Vasodilation, Internal medicine, Cardiology, Respiratory system
- MeSH
- humans, hyperventilation, fever, exercise, heating, acclimatization, body temperature regulation, sweating, homeostasis, plasma volume, cerebrovascular circulation, rest, adult, male, cold temperature, hot temperature, arterial pressure
5 authors
From JP, CA
- Naoto FujiiUniversity of Tsukuba; University of Ottawa
- Bun TsujiUniversity of Tsukuba
- Yasushi HondaUniversity of Tsukuba
- Narihiko KondoKobe University
- Takeshi Nishiyasu · correspondingUniversity of Tsukuba
Abstract
Hyperthermia induces hyperventilation and cerebral hypoperfusion in resting humans. We tested the hypothesis that short-term exercise-heat acclimation would alleviate those effects. Twenty healthy male subjects were divided into two groups that performed exercise training in the heat (TR-HEAT, n = 10) or cold (TR-COLD, n = 10). Before and after the training, the subjects in both groups participated in passive-heat tests at rest. Training was performed at 37°C (TR-HEAT) or 10°C (TR-COLD) and entailed four 20-min bouts of cycling at 50% peak oxygen uptake separated by 10-min recoveries daily for 6 consecutive days. After TR-HEAT, esophageal temperature was lowered when measured before and during passive heating, as was the esophageal temperature threshold for cutaneous active vasodilation, whereas plasma volume was increased (all P 0.05). TR-HEAT had no significant effect on passive heating-induced increases in minute ventilation, even when evaluated as the esophageal temperature threshold for increases in minute ventilation and the slope relating minute ventilation to esophageal temperature (all P > 0.05). By contrast, TR-HEAT attenuated the passive heating-induced reduction in the cerebral vascular conductance index (middle cerebral artery mean blood velocity/mean arterial pressure) (all P 0.05). These data suggest that in resting heated humans, short-term heat acclimation achieved through moderate-intensity exercise training (i.e., 50% peak oxygen uptake) in the heat does not influence hyperthermia-induced hyperventilation, but it does potentially attenuate cerebral hypoperfusion.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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