Implantable Self-Powered Low-Level Laser Cure System for Mouse Embryonic Osteoblasts' Proliferation and Differentiation
Tang W, Tian J, Zheng Q, Yan L, Wang J, Li Z, Wang ZL
ACS nano · 71 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- In vitro/mechanistic study (classified by our AI screen)
- Studied in
- Cells or lab samples
- Main outcome
- Mechanisms only
Who paid for it
- Funding
- Independent funding
- Government
- National Natural Science Foundation of China
- Government
- China Postdoctoral Science Foundation
- Government
- Natural Science Foundation of Beijing Municipality
- Government
- Beijing Municipal Science and Technology Commission
- Government
- Beijing Nova Program
- Government
- Thousands Talents program for pioneer researcher and his innovation team
- Grants
- Natural Science Foundation of Beijing Municipality (7132121); Beijing Nova Program (Z121103002512019); Natural Science Foundation of Beijing Municipality (4141002); Beijing Municipal Science and Technology Commission (Z131100006013004); National Natural Science Foundation of China (31200702); China Postdoctoral Science Foundation (2014M550031)
Based on 6 listed funder(s).
Publication
- Published
- 2015-07-10 · ACS Nano · vol. 9 · issue 8 · pp. 7867–7873
- Publisher
- American Chemical Society
- Cited
- 154 citations · more than 98% of similar papers · 7.4× the field average
- Impact
- Top 10% most cited in its field
- References
- 32 works
- Access
- Paywalled
- Research areas
- Advanced Sensor and Energy Harvesting Materials · Laser Applications in Dentistry and Medicine · Tactile and Sensory Interactions
- Keywords
- Embryonic stem cell, Bone remodeling, Osteoblast, Triboelectric effect, Bone healing, Materials science, Cell biology, Process (computing), Nanogenerator, Biomedical engineering, Nanotechnology, Medicine, Biology, Anatomy, Computer science, Internal medicine, In vitro
- MeSH
- cell line, osteoblasts, animals, humans, mice, infrared rays, cell differentiation, cell proliferation, osteogenesis, nanostructures, electric power supplies, embryo, mammalian, low-level light therapy
7 authors
From CN, US
- Wei Yieng TangChinese Academy of Sciences; Beijing Institute of Nanoenergy and Nanosystems
- Jingjing TianChinese Academy of Sciences; Beijing Institute of Nanoenergy and Nanosystems
- Qiang ZhengChinese Academy of Sciences; Beijing Institute of Nanoenergy and Nanosystems
- Lin Yuan YanBeihang University
- Jiangxue WangBeihang University
- Zhou Li · correspondingChinese Academy of Sciences; Beijing Institute of Nanoenergy and Nanosystems
Abstract
Bone remodeling or orthodontic treatment is usually a long-term process. It is highly desirable to speed up the process for effective medical treatment. In this work, a self-powered low-level laser cure system for osteogenesis is developed using the power generated by the triboelectric nanogenerator. It is found that the system significantly accelerated the mouse embryonic osteoblasts' proliferation and differentiation, which is essential for bone and tooth healing. The system is further demonstrated to be driven by a living creature's motions, such as human walking or a mouse's breathing, suggesting its practical use as a portable or implantable clinical cure for bone remodeling or orthodontic treatment.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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