Efficacy of low-level laser therapy for the treatment of burning mouth syndrome: a randomized, controlled trial
Spanemberg JC, López López J, de Figueiredo MA, Cherubini K, Salum FG
Journal of biomedical optics · 44 citations
How it was studied
- Design
- Randomized controlled trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- Government
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Government
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
Based on 2 listed funder(s).
Publication
- Published
- 2015-09-11 · J Biomed Opt · vol. 20 · issue 9 · p. 098001
- Publisher
- SPIE
- Cited
- 73 citations · more than 85% of similar papers · 1.8× the field average
- References
- 40 works
- Access
- Free to read
- Research areas
- Salivary Gland Disorders and Functions · Laser Applications in Dentistry and Medicine
- Keywords
- Randomized controlled trial, Low level laser therapy, Burning mouth syndrome, Medicine, Laser therapy, Dentistry, Laser, Internal medicine, Optics, Physics
- MeSH
- humans, burning mouth syndrome, pain measurement, aged, middle aged, female, male, low-level light therapy
5 authors
From BR, ES
- Juliana Cassol SpanembergPontifícia Universidade Católica do Rio Grande do Sul
- José López LópezBellvitge University Hospital; Universitat de Barcelona
- Maria Antonia Zancanaro de FigueiredoPontifícia Universidade Católica do Rio Grande do Sul
- Karen CherubiniPontifícia Universidade Católica do Rio Grande do Sul
- Fernanda Gonçalves SalumPontifícia Universidade Católica do Rio Grande do Sul
Abstract
The aim of the present study was to assess the effect of low-level laser therapy (LLLT) in the treatment of burning mouth syndrome (BMS). A diode laser was used in 78 BMS patients who were randomly assigned into four groups: IR1W, n = 20 (830 nm, 100 mW, 5 J, 176 J/cm2, 50 s, LLLT weekly sessions, 10 sessions); IR3W, n = 20 (830 nm, 100 mW, 5 J, 176 J/cm2, 50 s, three LLLT weekly sessions, 9 sessions); red laser, n = 19 (685 nm, 35 mW, 2 J, 72 J/cm2, 58 s, three LLLT weekly sessions, 9 sessions); and control-group (CG), n = 19. Symptoms were assessed at the end of the treatment and eight weeks later; quality of life related to oral health was assessed using the Oral Health Impact Profile (OHIP-14). Statistical analysis was carried out using repeated measures analysis of variance followed by the posthoc Tukey test. There was significant reduction of the symptoms in all groups at the end of the treatment, which was maintained in the follow-up. The scores of the IR1W and IR3W laser groups differed significantly from those of the CG. There was also a decrease in the OHIP-14 scores in the four groups. The IR3W laser group scores differed significantly from those of the CG. LLLT reduces the symptoms of BMS and may be an alternative therapeutic strategy for the relief of symptoms in patients with BMS.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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