Study2014Open access

A Study on the Association between Low Maternal Serum Magnesium Level and Preterm Labour

Okunade KS, Oluwole AA, Adegbesan-Omilabu MA

Advances in medicine · 8 citations

How it was studied

Design
Case-control study (classified by our AI screen)
Studied in
People
Main outcome
Clinical events such as disease or death

Who paid for it

Funding
Independent funding

Based on full-text disclosure statement.

Publication

Published
2014-01-01 · Adv Med · vol. 2014 · pp. 1–6
Publisher
Hindawi Publishing Corporation
Cited
29 citations · more than 56% of similar papers · 0.2× the field average
References
33 works
Access
Open access (hybrid journal) · CC-BY
Research areas
Preterm Birth and Chorioamnionitis · Pregnancy-related medical research · Pregnancy and preeclampsia studies
Keywords
Magnesium, Preterm labour, Medicine, Preterm labor, Obstetrics, Pregnancy, Gestation, Chemistry

3 authors

From NG

  • Kehinde S. Okunade · correspondingLagos University Teaching Hospital
  • Ayodeji Ayotunde OluwoleLagos University Teaching Hospital
  • Maymunah A. Adegbesan-OmilabuLagos University Teaching Hospital

Abstract

Objectives. The study was aimed to assess the association between low maternal serum magnesium levels and preterm labour. Methods. It is a cross-sectional case-control study in which eligible participants were pregnant women admitted in labour within the labour ward complex of a Lagos tertiary hospital. Relevant data were extracted from the case records of these women and blood samples were obtained from all participants and serum magnesium levels measured. Results. The study showed that 36% of the study patients had varying degrees of hypomagnesaemia. The relative risk indicates that preterm labour is 1.83 times higher among the patients with low serum magnesium (less than 1.6 mg/dL). The mean difference in serum magnesium levels in both groups was statistically significant (P<0.05). Conclusion. We can infer that low serum magnesium (hypomagnesaemia) is associated with preterm onset of labour. We can, also from this finding, formulate a proposition that would help in preventing preterm labour and birth with the use of prophylactic oral magnesium supplementation among patients with higher risk for development of preterm labour.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).

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