Funded in part by Egg Nutrition Center
Whole Egg Consumption Prevents Diminished Serum 25-Hydroxycholecalciferol Concentrations in Type 2 Diabetic Rats
Jones SK, Koh GY, Rowling MJ, Schalinske KL
Journal of agricultural and food chemistry · 8 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Animal study (classified by our AI screen)
- Studied in
- Animals
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Industry funded
- Industry group
- Egg Nutrition Center
Based on 1 listed funder(s).
Publication
- Published
- 2015-12-17 · J Agric Food Chem · vol. 64 · issue 1 · pp. 120–124
- Publisher
- American Chemical Society
- Cited
- 12 citations · more than 77% of similar papers · 1.1× the field average
- References
- 21 works
- Access
- Paywalled
- Research areas
- Vitamin D Research Studies · Diet and metabolism studies · Nutritional Studies and Diet
- Keywords
- Internal medicine, Endocrinology, Vitamin D and neurology, Type 2 diabetes, Casein, Hypertriglyceridemia, Diabetes mellitus, Vitamin, Medicine, Chemistry, Triglyceride, Cholesterol, Food science
- MeSH
- animals, humans, rats, rats, zucker, diabetes mellitus, type 2, disease models, animal, calcifediol, vitamin d, eggs, male
4 authors
From US
- Samantha K. JonesIowa State University
- Gar Yee KohIowa State University
- Matthew James RowlingIowa State University
- Kevin Lee Schalinske · correspondingIowa State University
Abstract
Type 2 diabetes (T2D) is characterized by vitamin D deficiency owing to increased urinary loss of 25-hydroxycholecalciferol (25D). Whole eggs are a rich source of vitamin D, particularly 25D, the circulating form that reflects status. Zucker diabetic (type 2) fatty (ZDF) rats and their lean counterparts were fed casein- or whole egg-based diets for 8 weeks. Whole egg consumption attenuated both hyperglycemia and hypertriglyceridemia, as well as reduced weight gain in ZDF rats compared to casein-fed diabetic rats. Circulating 25D was lower in casein-fed ZDF rats compared to lean controls; however, ZDF rats fed whole egg exhibited the same circulating 25D concentration as casein-fed lean rats. These data suggest that dietary whole egg can attenuate metabolic anomalies, as well as maintain normal circulating 25D concentrations in T2D rats. This finding may support new dietary recommendations targeting vitamin D deficiency prevention in T2D.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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