Association between nut consumption and coronary heart disease: a meta-analysis
Weng YQ, Yao J, Guo ML, Qin QJ, Li P
Coronary artery disease · 13 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Not stated
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2015-12-24 · Coron Artery Dis · vol. 27 · issue 3 · pp. 227–232
- Publisher
- Lippincott Williams & Wilkins
- Cited
- 15 citations · more than 75% of similar papers · 0.9× the field average
- References
- 33 works
- Access
- Paywalled
- Research areas
- Nuts composition and effects · Oral Health Pathology and Treatment · Botany, Ecology, and Taxonomy Studies
- Keywords
- Medicine, Relative risk, Nut, Confidence interval, Publication bias, Meta-analysis, Random effects model, Demography, Consumption (sociology), Coronary heart disease, Epidemiology, Internal medicine
- MeSH
- humans, nuts, coronary disease, linear models, odds ratio, risk assessment, risk factors, least-squares analysis, risk reduction behavior, time factors, recommended dietary allowances, protective factors, diet, healthy
5 authors
From CN
- Yunqi Weng · correspondingQingdao University
- Jian YaoQingdao University
- Minglei GuoQingdao University
- Qiaoji Qin · correspondingQingdao University
- Peng LiQingdao University
Abstract
Objectives
Epidemiological studies evaluating the association of nut consumption with coronary heart disease (CHD) risk have produced inconsistent results. The current study aimed to assess the CHD risk for the highest versus the lowest categories of nut consumption, the dose-response association of CHD for every 1 serving/week increment in nut consumption, and the heterogeneity among studies and publication bias.
Methods
Pertinent studies were identified by a search in PubMed and Web of Knowledge up to January 2014. A random-effect model was used to combine the results. The dose-response relationship was assessed by restricted cubic spline and variance-weighted least squares regression analysis. Publication bias was estimated using Egger's regression asymmetry test.
Results
Ten articles with 14 studies including 6302 CHD cases were included in this meta-analysis. Pooled results suggested that highest nut consumption amount versus lowest amount was associated significantly with a reduced risk of CHD [summary relative risk (RR)=0.681, 95% confidence interval (CI)=0.592-0.783, I(2)=62.7%], especially among USA (summary RR=0.671, 95% CI=0.591-0.761) and prospective studies (summary RR=0.660, 95% CI=0.581-0.748). A linear dose-response relationship was found, and the risk of CHD decreased by 10% for every 1 serving/week increase intake of nut (summary RR=0.90, 95% CI=0.87-0.94) No publication bias was found.
Conclusion
Our analysis suggested that higher nut consumption might have a protective effect on CHD risk, especially in the USA, which needs to be confirmed.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
Community trust
Loading…
How much do you trust this study's findings?
Comments
Sign in to rate, comment on or flag this study.Sign inSomething wrong here?
Flag this study if its information, labels or funding look wrong. An editor reviews every flag.
Sign in to rate, comment on or flag this study.Sign inEducational information about published research. Not medical advice, and not a recommendation to start or stop anything.