Effect of coffee (caffeine) against human cataract blindness
Varma SD
Clinical ophthalmology (Auckland, N.Z.) · 17 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cross-sectional study (classified by our AI screen)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2016-01-01 · Clin Ophthalmol · vol. 10 · p. 213
- Publisher
- Dove Medical Press
- Cited
- 32 citations · more than 89% of similar papers · 2.9× the field average
- References
- 81 works
- Access
- Open access (journal) · CC-BY-NC
- Research areas
- Coffee research and impacts · Advanced Glycation End Products research · Dye analysis and toxicity
- Keywords
- Caffeine, Medicine, Blindness, Incidence (geometry), Physiology, Ophthalmology, Animal studies, Optometry, Internal medicine
1 author
From US
- Shambhu D. Varma · correspondingUniversity of Maryland, Baltimore
Abstract
Previous biochemical and morphological studies with animal experiments have demonstrated that caffeine given topically or orally to certain experimental animal models has significant inhibitory effect on cataract formation. The present studies were undertaken to examine if there is a correlation between coffee drinking and incidence of cataract blindness in human beings. That has been found to be the case. Incidence of cataract blindness was found to be significantly lower in groups consuming higher amounts of coffee in comparison to the groups with lower coffee intake. Mechanistically, the caffeine effect could be multifactorial, involving its antioxidant as well as its bioenergetic effects on the lens.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY-NC).
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