Effect of Blueberry Anthocyanins Malvidin and Glycosides on the Antioxidant Properties in Endothelial Cells
Huang W, Zhu Y, Li C, Sui Z, Min W
Oxidative medicine and cellular longevity · 68 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- In vitro/mechanistic study (classified by our AI screen)
- Studied in
- Cells or lab samples
- Main outcome
- Mechanisms only
Who paid for it
- Funding
- Independent funding
- Government
- National Natural Science Foundation of China
- Government
- Government of Jiangsu Province
- Government
- Natural Science Foundation of Jiangsu Province
- Grants
- National Natural Science Foundation of China (BK20141386); Natural Science Foundation of Jiangsu Province (31101264); National Natural Science Foundation of China (31101264); Natural Science Foundation of Jiangsu Province (BK20141386); National Natural Science Foundation of China (31301419); Natural Science Foundation of Jiangsu Province (31301419)
Based on 3 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2016-01-01 · Oxid Med Cell Longev · vol. 2016 · issue 1 · p. 1591803
- Publisher
- Hindawi Publishing Corporation
- Cited
- 106 citations · more than 95% of similar papers · 3.9× the field average
- Impact
- Top 10% most cited in its field
- References
- 32 works
- Access
- Open access (hybrid journal) · CC-BY
- Research areas
- Phytochemicals and Antioxidant Activities · Antioxidant Activity and Oxidative Stress · Sirtuins and Resveratrol in Medicine
- Keywords
- Malvidin, Antioxidant, Chemistry, Reactive oxygen species, Superoxide dismutase, Biochemistry, Oxidative stress, Anthocyanin, Food science, Xanthine oxidase, Cyanidin, Enzyme
- MeSH
- cells, cultured, humans, reactive oxygen species, anthocyanins, glycosides, glucosides, antioxidants, oxidative stress, heme oxygenase-1, human umbilical vein endothelial cells, blueberry plants, superoxide dismutase-1
5 authors
From CN
- Wuyang HuangJiangsu Academy of Agricultural Sciences
- Yunming ZhuJiangsu Academy of Agricultural Sciences; Jilin Agricultural University
- Chunyang LiJiangsu Academy of Agricultural Sciences
- Zhongquan Sui · correspondingShanghai Jiao Tong University
- Weihong Min · correspondingJilin Agricultural University
Abstract
The objective of this research was to survey the antioxidant functional role of the main anthocyanins of blueberries in endothelial cells. Changes on the reactive oxygen species (ROS), xanthine oxidase-1 (XO-1), superoxide dismutase (SOD), and heme oxygenase-1 (HO-1) in cells of malvidin and the two glycosides were investigated. The results showed that these anthocyanins decreased the levels of ROS and XO-1 but increased the levels of SOD and HO-1. Glycosides improved the antioxidant capacity of malvidin to a great extent. The changes in the antioxidant properties of malvidin-3-glucoside were more pronounced than malvidin-3-galactoside. Variation in levels of malvidin-3-glucoside and malvidin-3-galactoside had a significant impact on antioxidant properties to different extents. It indicates that blueberries are a good resource of anthocyanins, which can protect cells from oxidative deterioration and use blueberry as a potential functional food to prevent diseases related to oxidative stress.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
Community trust
Loading…
How much do you trust this study's findings?
Comments
Sign in to rate, comment on or flag this study.Sign inSomething wrong here?
Flag this study if its information, labels or funding look wrong. An editor reviews every flag.
Sign in to rate, comment on or flag this study.Sign inEducational information about published research. Not medical advice, and not a recommendation to start or stop anything.