Efficacy of ozonized olive oil in the management of oral lesions and conditions: A clinical trial
Kumar T, Arora N, Puri G, Aravinda K, Dixit A, Jatti D
Contemporary clinical dentistry · 20 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cohort study (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Not stated
Who paid for it
- Funding
- Independent funding
Based on full-text disclosure statement.
Publication
- Published
- 2016-01-01 · Contemp Clin Dent · vol. 7 · issue 1 · pp. 51–54
- Publisher
- Medknow
- Cited
- 46 citations · more than 85% of similar papers · 2.0× the field average
- References
- 8 works
- Access
- Open access (journal) · CC-BY-NC-SA
- Research areas
- Medical and Biological Ozone Research · Oral Health Pathology and Treatment · Oral health in cancer treatment
- Keywords
- Olive oil, Medicine, Clinical trial, Randomized controlled trial, Traditional medicine, Surgery, Internal medicine, Food science, Chemistry
6 authors
From US, IN
- Tarun Kumar · correspondingCreative Commons; Swami Devi Dyal Hospital and Dental College; D.A.V Centenary Dental College
- Neha AroraCreative Commons; Swami Devi Dyal Hospital and Dental College; D.A.V Centenary Dental College
- Gagan PuriCreative Commons; Swami Devi Dyal Hospital and Dental College; D.A.V Centenary Dental College
- Aravinda KonidenaCreative Commons; Swami Devi Dyal Hospital and Dental College; D.A.V Centenary Dental College
- Avani DixitCreative Commons; Swami Devi Dyal Hospital and Dental College; D.A.V Centenary Dental College
- Deepa Jatti PatilCreative Commons; Swami Devi Dyal Hospital and Dental College; D.A.V Centenary Dental College
Abstract
Unlabelled
The oral cavity is an open ecosystem that shows a dynamic balance between the entrance of microorganisms (bacterial, viral or fungal), colonization modalities, nutritional balance, and host defenses against their removal. The oral lesions including aphthous ulcerations, herpes labialis, oral candidiasis, oral lichen planus, and angular cheilitis some of the common entities encountered in the clinical practice. A variety of treatment options is available in the literature for all of these lesions and conditions. Topical ozone therapy is a minimally invasive technique that can be used for these conditions without any side effects.
Aim and objectives
To evaluate the efficacy of ozonized olive oil in the treatment of oral lesions and conditions.
Materials and methods
A longitudinal study was carried out on 50 patients (aphthous ulcerations, herpes labialis, oral candidiasis, oral lichen planus, and angular cheilitis). The ozonized olive oil was applied twice daily until the lesion regresses for a maximum of 6 months.
Results
All the lesions regress in patients with aphthous ulcerations, herpes labialis, oral candidiasis and angular cheilitis or showed improvement in the signs and symptoms in oral lichen planus patients. No toxicity or side effect was observed in any of the patients.
Conclusion
Ozone therapy though requires a gaseous form to be more effective, but topical form can also bring out the positive results without any toxicity or side effect. Hence, it can be considered as a minimally invasive therapy for the oral infective and immunological conditions.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY-NC-SA).
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