Understanding the Impact of Omega-3 Rich Diet on the Gut Microbiota
Noriega BS, Sanchez-Gonzalez MA, Salyakina D, Coffman J
Case reports in medicine · 124 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Case report (classified by our AI screen)
- Studied in
- People
- Main outcome
- Mechanisms only
Who paid for it
- Funding
- Independent funding
Based on full-text disclosure statement.
Publication
- Published
- 2016-01-01 · Case Rep Med · vol. 2016 · issue 1 · p. 3089303
- Publisher
- Hindawi Publishing Corporation
- Cited
- 163 citations · more than 96% of similar papers · 5.2× the field average
- Impact
- Top 10% most cited in its field
- References
- 25 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Gut microbiota and health · Diet and metabolism studies · Nutritional Studies and Diet
- Keywords
- Faecalibacterium prausnitzii, Gut flora, Butyrate, Akkermansia, Akkermansia muciniphila, Gut bacteria, Medicine, Microbiome, Bifidobacterium, Physiology, Gut microbiome, Feces, Biology, Immunology, Bacteroides, Lactobacillus, Bacteria, Microbiology, Bioinformatics, Food science
4 authors
From US
- Blanca S. Noriega EsquivesLarkin Community Hospital
- Marcos A. Sanchez‐Gonzalez · correspondingLarkin Community Hospital
- Daria SalyakinaUniversity of Miami
- Jonathan A. Coffman
Abstract
Background. Recently, the importance of the gut microbiota in the pathogenesis of several disorders has gained clinical interests. Among exogenous factors affecting gut microbiome, diet appears to have the largest effect. Fatty acids, especially omega-3 polyunsaturated, ameliorate a range of several diseases, including cardiometabolic and inflammatory and cancer. Fatty acids associated beneficial effects may be mediated, to an important extent, through changes in gut microbiota composition. We sought to understand the changes of the gut microbiota in response to an omega-3 rich diet. Case Presentation. This case study investigated changes of gut microbiota with an omega-3 rich diet. Fecal samples were collected from a 45-year-old male who consumed 600 mg of omega-3 daily for 14 days. After the intervention, species diversity was decreased, but several butyrate-producing bacteria increased. There was an important decrease in Faecalibacterium prausnitzii and Akkermansia spp. Gut microbiota changes were reverted after the 14-day washout. Conclusion. Some of the health-related benefits of omega-3 may be due, in part, to increases in butyrate-producing bacteria. These findings may shed light on the mechanisms explaining the effects of omega-3 in several chronic diseases and may also serve as an existing foundation for tailoring personalized medical treatments.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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