Impact of creatine supplementation in combination with resistance training on lean mass in the elderly
Pinto CL, Botelho PB, Carneiro JA, Mota JF
Journal of cachexia, sarcopenia and muscle · 66 citations
How it was studied
- Design
- Randomized controlled trial (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- Government
- Fundação de Amparo à Pesquisa do Estado de Goiás
Based on 1 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2016-01-18 · J Cachexia Sarcopenia Muscle · vol. 7 · issue 4 · pp. 413–421
- Publisher
- Springer Science+Business Media
- Cited
- 102 citations · more than 97% of similar papers · 5.9× the field average
- Impact
- Top 10% most cited in its field
- References
- 43 works
- Access
- Open access (journal) · CC-BY-NC-ND
- Research areas
- Muscle metabolism and nutrition · Nutrition and Health in Aging · Cardiovascular and exercise physiology
- Keywords
- Lean body mass, Medicine, Bench press, Creatine, Creatine Monohydrate, Leg press, Bone mineral, Placebo, One-repetition maximum, Resistance training, Dual-energy X-ray absorptiometry, Femoral neck, Physical therapy, Ageing, Internal medicine, Strength training, Bone density, Osteoporosis, Body weight, Pathology
4 authors
From BR
- Camila Lemos PintoUniversidade Federal de Goiás
- Patrícia Borges BotelhoUniversidade Federal de Goiás
- Juliana Alves CarneiroUniversidade Federal de Goiás
- João Felipe Mota · correspondingUniversidade Federal de Goiás
Abstract
Background
Human ageing is a process characterized by loss of muscle mass, strength, and bone mass. We aimed to examine the efficacy of low-dose creatine supplementation associated with resistance training on lean mass, strength, and bone mass in the elderly.
Methods
This was a 12-week, parallel-group, double-blind, randomized, placebo-controlled trial. The individuals were randomly allocated into one of the following groups: placebo plus resistance training (PL + RT) and creatine supplementation plus resistance training (CR + RT) . The participants were assessed at baseline and after 12 weeks. The primary outcomes were lean mass and strength, assessed by dual energy X-ray absorptiometry (DXA) and ten-repetition maximal tests (10 RM), respectively. Secondary outcomes included the lumbar spine, right and left femoral neck, both femur and whole body bone mineral density (BMD), and whole body bone mineral content (BMC), assessed by DXA.
Results
The CR + RT group had superior gains in lean mass when compared with the PL + RT group (P = 0.02). Changes in the 10 RM tests in bench press and leg press exercises, body composition, BMD, and BMC of all assessed sites did not significantly differ between the groups (P > 0.05).
Conclusions
Twelve weeks of low-dose creatine supplementation associated with resistance training resulted in increases in lean mass in the elderly.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY-NC-ND).
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