Study2016

Low Level Laser Therapy Versus Pharmacotherapy in Improving Myofascial Pain Disorder Syndrome

Khalighi HR, Mortazavi H, Mojahedi SM, Azari-Marhabi S, Moradi Abbasabadi F

Journal of lasers in medical sciences · 36 citations

How it was studied

Design
Randomized controlled trial (classified by our AI screen)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Independent funding
University or hospital
Shahid Beheshti University of Medical Sciences

Based on 1 listed funder(s).

Publication

Published
2016-01-07 · J Lasers Med Sci · vol. 7 · issue 1 · pp. 45–50
Cited
118 citations · more than 98% of similar papers · 8.5× the field average
Impact
Top 10% most cited in its field
References
29 works
Access
Open access (free to publish) · CC-BY-NC
Research areas
Temporomandibular Joint Disorders · Laser Applications in Dentistry and Medicine · Myofascial pain diagnosis and treatment
Keywords
Medicine, Low level laser therapy, Visual analogue scale, Placebo, Burning mouth syndrome, Pharmacotherapy, Anesthesia, Randomized controlled trial, Physical therapy, Laser therapy, Internal medicine, Laser

5 authors

From IR

  • Hamid Reza KhalighiShahid Beheshti University of Medical Sciences
  • Hamed MortazaviShahid Beheshti University of Medical Sciences
  • Seyed Masoud MojahediShahid Beheshti University of Medical Sciences
  • Saranaz Azari-MarhabiShahid Beheshti University of Medical Sciences
  • Faranak Moradi AbbasabadiQom University of Medical Science and Health Services

Abstract

Introduction

Temporomandibular disorders (TMD) lead to masticatory muscle pain, jaw movement disability and limitation in mouth opening. Pain is the chief complaint in 90% of the TMD patients which leads to disability and severe socioeconomic costs. The purpose of this study was to evaluate the therapeutic effects of low level laser therapy (LLLT) compared to pharmacotherapy with NSAIDs (naproxen) in myofascial pain disorder syndrome (MPDS).

Methods

In this randomized controlled clinical trial, 40 MPDS patients were divided into two groups. One group received naproxen 500 mg bid for 3 weeks as treatment modality and also had placebo laser sessions. The other group received active laser (diode 810 nm CW) as treatment and placebo drug. Pain intensity was measured by visual analogue scale (VAS) and maximum painless mouth opening was also measured as a functional index every session and at 2 months follow up. Data was collected and analyzed with SPSS software. Independent t test was used to analyze the data. A P < 0.05 was considered significant.

Results

Low level laser caused significant reduction in pain intensity (P < 0.05) and a significant increase in mouth opening. In naproxen group neither pain intensity nor maximum mouth opening had significant improvement. Pain relief, in subjective VAS was observed in third session in LLLT group, but did not occur in naproxen group. Maximum mouth opening increased significantly in laser group compared to the naproxen group from the eighth session.

Conclusion

Treatment with LLLT caused a significant improvement in mouth opening and pain intensity in patients with MPDS. Similar improvement was not observed in naproxen group.

Abstract via Europe PMC. Copyright remains with the authors or publisher.

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