Thermoregulatory responses to combined moderate heat stress and hypoxia
Low DA, Bailey TG, Timothy Cable N, Jones H
Microcirculation (New York, N.Y. : 1994) · 7 citations
How it was studied
- Design
- Controlled clinical trial (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- Government
- Seventh Framework Programme
- Grants
- Seventh Framework Programme (239143)
Based on 1 listed funder(s).
Publication
- Published
- 2016-07-15 · Microcirculation · vol. 23 · issue 7 · pp. 487–494
- Publisher
- Wiley
- Cited
- 7 citations · more than 69% of similar papers · 0.6× the field average
- References
- 40 works
- Access
- Free to read
- Research areas
- Thermoregulation and physiological responses · Thermal Regulation in Medicine · Infrared Thermography in Medicine
- Keywords
- Medicine, Hypoxia (environmental), Forearm, Internal medicine, Thermoregulation, Sudomotor, Heart rate, Cardiology, Skin temperature, SWEAT, Core temperature, Endocrinology, Anesthesia, Blood pressure, Oxygen, Surgery, Chemistry, Biomedical engineering
- MeSH
- forearm, thorax, skin, humans, body temperature regulation, sweating, skin temperature, heat-shock response, regional blood flow, adult, male, young adult, hypoxia
4 authors
From GB, QA
- David A. Low · correspondingLiverpool John Moores University
- Tom G. BaileyLiverpool John Moores University
- Nigel Timothy CableAspire Academy; Liverpool John Moores University
- Helen E JonesLiverpool John Moores University
Abstract
Objective
The aim of this study was to examine the cutaneous vascular and sudomotor responses to combined moderate passive heat stress and normobaric hypoxia.
Method
Thirteen healthy young males, dressed in a water-perfused suit, underwent passive heating (Δcore temperature ~0.7°C) twice (Normoxia; 20.9% O2 and Hypoxia; 13% O2 ). Chest and forearm skin blood flow (SkBF; laser-Doppler flux) and sweat rate (SR; capacitance hygrometry), core (intestinal pill), and skin temperatures, were recorded.
Results
Hypoxia reduced baseline oxygen saturation (98±1 vs 89±6%, P-1 , P<.01). During heating, mean body temperature (T¯BODY) thresholds for SkBF (P=.41) and SR (P=.28) elevations were not different between trials. The SkBF: T¯BODY linear sensitivity during the initial phase of heating was lower at the chest (P=.035) but not different at the forearm (P=.17) during hypoxia. With increasing levels of heating chest SkBF was not different (P=.55) but forearm SkBF was lower (P<.01) during hypoxia. Chest (P=.85) and forearm (P=.79) SR: T¯BODY linear sensitivities were not different between trials.
Conclusion
While sudomotor responses and the initiation of cutaneous blood flow elevations are unaffected, hypoxia differentially effects regional SkBF responses during moderate passive heating.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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