Systematic review2016

Management of recurrent aphthous ulcers using low-level lasers: A systematic review

Najeeb S, Khurshid Z, Zohaib S, Najeeb B, Qasim SB, Zafar MS

Medicina (Kaunas, Lithuania) · 19 citations

Review labels

Funding not disclosed

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Systematic review (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Funding not disclosed

Publication

Published
2016-01-01 · Medicina (Kaunas) · vol. 52 · issue 5 · pp. 263–268
Publisher
Multidisciplinary Digital Publishing Institute
Cited
53 citations · more than 59% of similar papers · 0.8× the field average
References
42 works
Access
Open access (journal) · CC-BY-NC-ND
Research areas
Oral Health Pathology and Treatment · Laser Applications in Dentistry and Medicine · Dermatologic Treatments and Research
Keywords
Medicine, Recurrent aphthous stomatitis, MEDLINE, Randomized controlled trial, Clinical trial, Etiology, Meta-analysis, Systematic review, Stomatitis, Physical therapy, Dermatology, Intensive care medicine, Surgery, Internal medicine
MeSH
humans, stomatitis, aphthous, time factors, adult, middle aged, randomized controlled trials as topic, lasers, gas, chronic pain, low-level light therapy

6 authors

From SA, GB

  • Shariq NajeebAl-Farabi College
  • Zohaib KhurshidKing Faisal University
  • Sana ZohaibKing Faisal University
  • Bilal NajeebRiyadh Elm University
  • Syed Saad Bin QasimUniversity of Sheffield
  • Muhammad Sohail Zafar · correspondingTaibah University

Abstract

Background and objective

The exact etiology of recurrent aphthous ulcers (RAS) is unknown. The management of RAS is not always straightforward. The aim of this review is to critically analyze and summarize the clinical literature focusing on the management of aphthous ulcers using low-level lasers.

Materials and methods

The Medline (PubMed), Web of Knowledge (ISI), Cochrane Central Register of Controlled Trials (CENTRAL) and Embase databases were searched electronically for studies published in last 20 years (1995-2015) using the keywords "recurrent aphthous stomatitis," "aphthous ulcers," and "laser."

Results

A total of 85 articles were found during the initial search; 76 studies were excluded for not fulfilling the criteria whereas nine studies were deemed suitable for this review. Among the included studies, two articles were case reports and seven were randomized clinical trials. Study design, sample size, type of intervention and control of each study were critically analyzed and summarized according to the CONSORT protocol. In majority of the patients, immediate pain relief and accelerated ulcer healing was observed following irradiation with lasers.

Conclusions

Although various types of lasers have succeeded in providing immediate pain relief to patients, carbon dioxide (CO2) lasers have the unique advantage of requiring a short exposure time (5-10s). In order to ascertain the efficacy of laser for treating ulcers in the clinical setting, more clinical trials are required.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY-NC-ND).

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