Randomized controlled trial2017

Creatine Monohydrate Supplementation Does Not Augment Fitness, Performance, or Body Composition Adaptations in Response to Four Weeks of High-Intensity Interval Training in Young Females

Forbes SC, Sletten N, Durrer C, Myette-Côté É, Candow D, Little JP

International journal of sport nutrition and exercise metabolism · 17 citations

Review labels

Funding not disclosed

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Randomized controlled trial (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Funding not disclosed

Publication

Published
2016-10-21 · Int J Sport Nutr Exerc Metab · vol. 27 · issue 3 · pp. 285–292
Publisher
Human Kinetics
Cited
30 citations · more than 86% of similar papers · 1.3× the field average
References
0 works
Access
Paywalled
Research areas
Cardiovascular and exercise physiology · Sports Performance and Training · Muscle metabolism and nutrition
Keywords
Cardiorespiratory fitness, High-intensity interval training, Interval training, Medicine, Lean body mass, Augment, Internal medicine, Placebo, Animal science, Endocrinology, Aerobic exercise, Physical therapy, Biology, Body weight
MeSH
humans, insulin resistance, creatine, exercise test, adaptation, physiological, body composition, oxygen consumption, dietary supplements, adult, female, young adult, sports nutritional physiological phenomena, cardiorespiratory fitness, high-intensity interval training

6 authors

  • Scott C. Forbes · corresponding
  • Nathan R. Sletten
  • Cody Garett Durrer
  • Étienne Myette‐Côté
  • Darren Glenn Candow
  • Jonathan P. Little

Abstract

High-intensity interval training (HIIT) has been shown to improve cardiorespiratory fitness, performance, body composition, and insulin sensitivity. Creatine (Cr) supplementation may augment responses to HIIT, leading to even greater physiological adaptations. The purpose of this study was to determine the effects of 4 weeks of HIIT (three sessions/week) combined with Cr supplementation in recreationally active females. Seventeen females (age = 23 ± 4 yrs; BMI = 23.4 ± 2.4) were randomly assigned to either Cr (Cr; 0.3 g・kg-1・d-1 for 5 d followed by 0.1 g・kg-1・d-1 for 23 days; n = 9) or placebo (PLA; n = 8). Before and after the intervention, VO2peak, ventilatory threshold (VT), time-trial performance, lean body mass and fat mass, and insulin sensitivity were assessed. HIIT improved VO2peak (Cr = +10.2%; PLA = +8.8%), VT (Cr = +12.7%; PLA = +9.9%), and time-trial performance (Cr = -11.5%; PLA = -11.6%) with no differences between groups (time main effects, all p < .001). There were no changes over time for fat mass (Cr = -0.3%; PLA = +4.3%), whole-body lean mass (Cr = +0.5%; PLA = -0.9%), or insulin resistance (Cr = +3.9%; PLA = +18.7%). In conclusion, HIIT is an effective way to improve cardiorespiratory fitness, VT, and time-trial performance. The addition of Cr to HIIT did not augment improvements in cardiorespiratory fitness, performance or body composition in recreationally active females.

Abstract via Europe PMC. Copyright remains with the authors or publisher.

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