Randomized controlled trial2017

Effects of low-level laser therapy on burning mouth syndrome

Valenzuela S, Lopez-Jornet P

Journal of oral rehabilitation · 33 citations

How it was studied

Design
Randomized controlled trial (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Independent funding
University or hospital
Universidad de Murcia

Based on 1 listed funder(s).

Publication

Published
2016-11-28 · J Oral Rehabil · vol. 44 · issue 2 · pp. 125–132
Publisher
Wiley
Cited
61 citations · more than 79% of similar papers · 1.1× the field average
References
23 works
Access
Paywalled
Research areas
Salivary Gland Disorders and Functions · Laser Applications in Dentistry and Medicine · Temporomandibular Joint Disorders
Keywords
Visual analogue scale, Placebo, Medicine, Low level laser therapy, Burning mouth syndrome, Randomized controlled trial, Laser therapy, Placebo group, Anesthesia, Laser, Dentistry, Internal medicine
MeSH
humans, burning mouth syndrome, xerostomia, treatment outcome, prospective studies, radiation dosage, adult, aged, aged, 80 and over, middle aged, spain, female, male, lasers, semiconductor, visual analog scale, low-level light therapy

2 authors

From ES

  • Sara ValenzuelaHospital General Universitario Morales Meseguer; Universidad de Murcia
  • Pía López‐Jornet · correspondingHospital General Universitario Morales Meseguer; Instituto Murciano de Investigación Biosanitaria; Universidad de Murcia

Abstract

To investigate low-level laser therapy (LLLT) applied to treat burning mouth syndrome (BMS). This prospective, comparative, partially blinded, single-centre, clinical trial of GaAlAs Laser, with 815 nm wavelength, included 44 BMS patients divided randomly into three groups: Group I (n = 16): GaAlAs laser 815 nm wavelength, 1 W output power, continuous emissions, 4 s, 4 J and fluence rate 133·3 J cm-2 ; Group II (n = 16): GaAlAs infrared laser, 815 nm wavelength, 1 W output power, continuous emissions, 6 s, 6 J and fluence rate 200 J cm-2 ; Group III (n = 12) placebo group, sham laser. All groups received a weekly dose for 4 weeks. Pain intensity was recorded using a 10-cm visual analogue scale; patients responded to the oral health impact profile (OHIP-14), xerostomia severity test and the hospital anxiety-depression scale (HAD). These assessments were performed at baseline, 2 and 4 weeks. LLLT decreased pain intensity and improved OHIP-14 scores significantly from baseline to 2 weeks in groups I and II compared with the placebo group. No statistically significant differences were found from 2 to 4 weeks. Overall improvements in visual analogue scale (VAS) scores from baseline to the end of treatment were as follows: Group I 15·7%; Group II 15·6%; Group III placebo 7·3%. LLLT application reduces symptoms slightly in BMS patients.

Abstract via Europe PMC. Copyright remains with the authors or publisher.

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